Recombinant Proteins
Product List
C20ORF20 Human
Chromosome 20 Open Reading Frame 20 Human Recombinant
C20ORF20 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
C6ORF108 Human
Chromosome 6 Open Reading Frame 108 Human Recombinant
C6ORF108 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
C7ORF49 Human
Chromosome 7 Open Reading Frame 49 Human Recombinant
C7ORF49 Human Recombinant produced in E. coli is a single polypeptide chain containing 180 amino acids (1-157) and having a molecular mass of 19.2kDa. C7ORF49 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
C9ORF103 Human
Chromosome 9 Open Reading Frame 103 Human Recombinant
C9ORF103 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
C9ORF95 Human
Chromosome 9 Open Reading Frame 95 Human Recombinant
C9ORF95 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
SF20 Human
Chromosome 19 Open Reading Frame 10 Human Recombinant
SF20 Mouse
Chromosome 19 Open Reading Frame 10 Mouse Recombinant
VTA1 Human
Vps20-Associated 1 Homolog Human Recombinant
VTA1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction
An open reading frame (ORF) is a sequence of DNA that starts with a start codon (usually AUG) and ends with a stop codon (UAA, UAG, or UGA). It is a segment of DNA that can be transcribed into RNA and translated into a protein. ORFs are crucial for identifying potential protein-coding regions within a genome .
Key Biological Properties: ORFs are essential for gene prediction and annotation. They are used to identify potential protein-coding genes within a DNA sequence .
Expression Patterns: ORFs can be found in various regions of the genome, including coding and non-coding regions. They are transcribed into mRNA, which is then translated into proteins by ribosomes .
Tissue Distribution: The expression of ORFs can vary across different tissues and developmental stages. Some ORFs are ubiquitously expressed, while others are tissue-specific .
Primary Biological Functions: ORFs encode proteins that perform various functions within the cell, including enzymatic activities, structural roles, and regulatory functions .
Role in Immune Responses: Some ORFs encode proteins involved in immune responses, such as cytokines and receptors that recognize and respond to pathogens .
Pathogen Recognition: ORFs can encode proteins that recognize and bind to pathogen-associated molecular patterns (PAMPs), initiating immune responses .
Mechanisms with Other Molecules and Cells: ORFs encode proteins that interact with other molecules and cells through various mechanisms, including binding to receptors, forming complexes, and participating in signaling pathways .
Binding Partners: Proteins encoded by ORFs can have specific binding partners, such as other proteins, nucleic acids, or small molecules, which are crucial for their function .
Downstream Signaling Cascades: ORF-encoded proteins can activate downstream signaling cascades, leading to various cellular responses, such as gene expression, cell proliferation, and apoptosis .
Transcriptional Regulation: The expression of ORFs is regulated at the transcriptional level by various factors, including transcription factors, enhancers, and silencers .
Post-Translational Modifications: ORF-encoded proteins can undergo post-translational modifications, such as phosphorylation, ubiquitination, and glycosylation, which can affect their stability, localization, and activity .
Biomedical Research: ORFs are used in biomedical research to study gene function, protein interactions, and disease mechanisms .
Diagnostic Tools: ORFs can be used as biomarkers for diagnosing diseases, such as cancer and genetic disorders .
Therapeutic Strategies: ORFs are targeted in therapeutic strategies, such as gene therapy and the development of small molecule inhibitors .
Development: ORFs play a crucial role in development by encoding proteins that regulate cell differentiation, growth, and morphogenesis .
Aging: The expression and function of ORFs can change with aging, affecting cellular processes and contributing to age-related diseases .
Disease: Mutations or dysregulation of ORFs can lead to various diseases, including cancer, neurodegenerative disorders, and metabolic diseases .
