C20ORF20 Human
Description
C20ORF20 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Specs
Product Science Overview
Chromosome 20 Open Reading Frame 20 (C20orf20) is a gene located on the long arm of chromosome 20. It is part of a larger family of open reading frames (ORFs) that are crucial for various biological processes. The human recombinant form of C20orf20 is a synthesized version of the protein encoded by this gene, produced through recombinant DNA technology.
C20orf20 is situated on chromosome 20, which is one of the 23 pairs of chromosomes in humans. The gene spans a specific region on the chromosome and includes several exons and introns. The exact nucleotide sequence and the arrangement of these exons and introns are critical for the gene’s function and regulation .
The primary function of C20orf20 is not fully understood, but it is believed to play a role in various cellular processes. Open reading frames like C20orf20 are segments of DNA that can be transcribed into RNA and then translated into proteins. These proteins are essential for numerous cellular functions, including cell growth, differentiation, and response to environmental signals .
The human recombinant form of C20orf20 is produced using recombinant DNA technology. This involves inserting the gene encoding C20orf20 into a suitable expression vector, which is then introduced into a host cell (such as bacteria or yeast). The host cells express the protein, which can be harvested and purified for various applications. Recombinant proteins are widely used in research, diagnostics, and therapeutic applications .
The expression of C20orf20 is regulated at multiple levels, including transcriptional, post-transcriptional, and post-translational modifications. Transcription factors bind to specific regions of the gene to initiate or suppress transcription. Additionally, microRNAs and other regulatory RNAs can modulate the stability and translation of the mRNA transcript. Post-translational modifications, such as phosphorylation and glycosylation, further regulate the activity and stability of the protein .
While the exact clinical significance of C20orf20 is still under investigation, alterations in its expression or function could potentially be linked to various diseases. Understanding the role of C20orf20 in normal and pathological conditions could provide insights into novel therapeutic targets and diagnostic markers .
