Recombinant Proteins
Product List
SURF1 Human
Surfeit-1 Human Recombinant
SURF2 Human
Surfeit-2 Human Recombinant
Introduction
Key Biological Properties: The Surfeit genes encode proteins with diverse functions. For instance, SURF6 is a nucleolar protein involved in ribosome biogenesis .
Expression Patterns: These genes are ubiquitously expressed in various tissues, indicating their fundamental roles in cellular functions .
Tissue Distribution: Surfeit proteins are found in multiple tissues, including the liver, brain, and heart, reflecting their involvement in essential physiological processes .
Primary Biological Functions: Surfeit proteins play crucial roles in ribosome biogenesis, protein trafficking, and lipid metabolism .
Role in Immune Responses and Pathogen Recognition: Some Surfeit proteins, like SURF4, are involved in the secretion of immune-related molecules, thereby contributing to immune responses .
Mechanisms with Other Molecules and Cells: Surfeit proteins interact with various cellular components. For example, SURF4 functions as a cargo receptor, mediating the transport of proteins between the endoplasmic reticulum and the Golgi apparatus .
Binding Partners and Downstream Signaling Cascades: SURF6 binds to both DNA and RNA, suggesting its role in nucleic acid metabolism . These interactions often trigger downstream signaling pathways that regulate cell growth and differentiation .
Transcriptional Regulation: The expression of Surfeit genes is tightly regulated at the transcriptional level to ensure proper cellular function .
Post-Translational Modifications: Surfeit proteins undergo various post-translational modifications, such as phosphorylation, which modulate their activity and stability .
Biomedical Research: Surfeit proteins are studied for their roles in diseases like cancer and neurodegenerative disorders .
Diagnostic Tools: The expression levels of Surfeit genes can serve as biomarkers for certain diseases .
Therapeutic Strategies: Targeting Surfeit proteins offers potential therapeutic avenues for treating metabolic and infectious diseases .
