Growth Factors
CD Antigens
Enzymes
Viral Antigens
Recombinant Proteins
Natural Proteins
Monoclonal Antibodies
Cytokines
Polyclonal Antibodies
Neurotrophins
Chemokines
Hormones
Recombinant Proteins
Product List
RB1 Human
Retinoblastoma Associated Protein Human Recombinant
Retinoblastoma Human Recombinant fused with 6X His tag produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 146 amino acids and having a molecular mass of 16.5 kDa.
The Retinoblastoma is purified by proprietary chromatographic techniques.
The Retinoblastoma is purified by proprietary chromatographic techniques.
Shipped with Ice Packs 
Cat. No.
BT14178
Source
Escherichia Coli.
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
RBBP4 Human
Retinoblastoma Binding Protein 4 Human Recombinant
RBBP4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 449 amino acids (1-425 a.a) and having a molecular mass of 50.2kDa.
RBBP4 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
RBBP4 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Shipped with Ice Packs
RBBP9 Human
Retinoblastoma Binding Protein 9 Human Recombinant
RBBP9 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 206 amino acids (1-186 a.a.) and having a molecular mass of 23.1kDa.
RBBP9 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
RBBP9 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Shipped with Ice Packs
Introduction
Definition and Classification
Retinoblastoma is the most common malignant intraocular tumor in children, primarily affecting the retina . It can be classified into two main types based on its presentation:
- Unilateral Retinoblastoma: Affects one eye and constitutes about 60-75% of cases .
- Bilateral Retinoblastoma: Affects both eyes and is almost always hereditary .
Retinoblastoma can also be classified based on its spread:
Biological Properties
Biological Functions
The primary biological functions of the retinoblastoma protein (pRB) include:
Modes of Action
The mechanisms of action of pRB involve interactions with various molecules and cells:
Regulatory Mechanisms
The expression and activity of pRB are controlled by several regulatory mechanisms:
Applications
Retinoblastoma has several applications in biomedical research, diagnostics, and therapeutics:
- Biomedical Research: Advances in genetics and molecular biology have improved our understanding of retinoblastoma .
- Diagnostic Tools: Molecular markers and genomic analysis aid in early detection and prognosis .
- Therapeutic Strategies: Targeted therapies, gene therapy, and novel drugs are being explored for treating retinoblastoma .
