C9ORF103 Human

Chromosome 9 Open Reading Frame 103 Human Recombinant
Cat. No.
BT10030
Source
E.coli.
Synonyms
Chromosome 9 open reading frame 103, bA522I20.2, Gluconate kinase, glucokinase-like protein, probable gluconokinase, GNTK, EC 2.7.1.12.
Appearance
Sterile Filtered colorless solution.
Purity
Greater than 95% as determined by SDS-PAGE.
Usage
THE BioTek's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Shipped with Ice Packs
In Stock

Description

C9ORF103 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 211 amino acids (1-187) and having a molecular mass of 23.1kDa.
C9ORF103 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Product Specs

Introduction
C9orf103, a member of the gluconokinase gntK/gntV family, plays a role in carbohydrate acid metabolism and D-gluconate degradation.
Description
Recombinant C9ORF103, expressed in E. coli, is a non-glycosylated polypeptide chain with a molecular weight of 23.1 kDa. This protein consists of 211 amino acids, including a 24 amino acid His-tag at the N-terminus (amino acids 1-187). Purification is achieved using proprietary chromatographic techniques.
Physical Appearance
Sterile, colorless solution.
Formulation
The C9ORF103 solution is provided at a concentration of 0.5 mg/ml and contains the following components: 20 mM Tris-HCl buffer (pH 8.0), 100 mM NaCl, 1 mM DTT, and 20% glycerol.
Stability
For short-term storage (2-4 weeks), keep at 4°C. For extended periods, store frozen at -20°C. Adding a carrier protein (0.1% HSA or BSA) is recommended for long-term storage. Avoid repeated freeze-thaw cycles.
Purity
Purity exceeds 95% as determined by SDS-PAGE analysis.
Synonyms
Chromosome 9 open reading frame 103, bA522I20.2, Gluconate kinase, glucokinase-like protein, probable gluconokinase, GNTK, EC 2.7.1.12.
Source
E.coli.
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMAAPGA LLVMGVSGSG KSTVGALLAS ELGWKFYDAD DYHPEENRRK MGKGIPLNDQ DRIPWLCNLH DILLRDVASG QRVVLACSAL KKTYRDILTQ GKDGVALKCE ESGKEAKQAE MQLLVVHLSG SFEVISGRLL KREGHFMPPE LLQSQFETL PPAAPENFIQ ISVDKNVSEI IATIMETLKM K

Product Science Overview

Gene and Protein Structure

C9ORF103 is characterized by its unique sequence and structure. The gene consists of several exons and introns, which are segments of DNA that are transcribed into RNA. The exons are the coding regions that are ultimately translated into the protein, while the introns are non-coding regions that are spliced out during RNA processing.

The protein encoded by C9ORF103 has a specific amino acid sequence that determines its structure and function. The recombinant form of this protein is produced by inserting the gene into a suitable expression system, such as bacteria or yeast, which then synthesizes the protein.

Biological Functions

The exact biological functions of C9ORF103 are still under investigation. However, proteins encoded by open reading frames often play crucial roles in various cellular processes, including:

  • Cell signaling: Proteins can act as messengers that transmit signals within and between cells.
  • Gene regulation: Some proteins are involved in regulating the expression of other genes.
  • Metabolic pathways: Proteins can function as enzymes that catalyze biochemical reactions.
Research and Applications

Recombinant C9ORF103 is used in various research applications to understand its role in human biology and disease. Some potential areas of research include:

  • Cancer research: Investigating the role of C9ORF103 in cancer development and progression.
  • Genetic disorders: Studying mutations in the C9ORF103 gene that may be associated with genetic diseases.
  • Drug development: Screening for compounds that interact with the C9ORF103 protein as potential therapeutic agents.

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