Enzymes
Product List
BCAT1 Human
Branched Chain Amino-Acid Transaminase 1 Human Recombinant
BCAT1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
BCAT2 Human
Branched Chain Amino-Acid Transaminase 2 Human Recombinant
BCAT2 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
GFPT1 Human
Glutamine--Fructose-6-Phosphate Transaminase 1 Human Recombinant
GFPT1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 391 amino acids (332-699 a.a) and having a molecular mass of 43.7kDa.
GFPT1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
GOT1 Human
Glutamic-Oxaloacetic Transaminase 1 Human Recombinant
GOT1 Human, Active
Glutamic-Oxaloacetic Transaminase 1 Human Recombinant, Active
GOT1 Mouse
Glutamic-Oxaloacetic Transaminase 1 Mouse Recombinant
GOT2 Human
Glutamic-Oxaloacetic Transaminase 2 Human Recombinant
GOT2 Human, Active
Glutamic-Oxaloacetic Transaminase 2 Human Recombinant, Active
GOT2 Mouse
Glutamic-Oxaloacetic Transaminase 2 Mouse Recombinant
GOT2 Recombinant Mouse produced in E.Coli is a single, non-glycosylated polypeptide chain containing 424 amino acids (30-430 a.a.) and having a molecular mass of 46.8kDa. Mouse GOT2 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
GOT2 Mouse, Active
Glutamic-Oxaloacetic Transaminase 2, Active Mouse Recombinant
GOT2 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 422 amino acids (30-430 aa) and having a molecular mass of 46.8kDa.
GOT2 is fused to a 21 amino acid His tag at N-terminus and purified by proprietary chromatographic techniques.
Escherichia Coli.
Introduction
Transaminases, also known as aminotransferases, are enzymes that catalyze the transfer of an amino group from an amino acid to a keto acid. This process is known as transamination. Transaminases are crucial for the synthesis of amino acids, which are the building blocks of proteins . They are classified based on the specific amino/keto acid pairs they act upon. For example, alanine transaminase (ALT) and aspartate transaminase (AST) are two well-known types .
Transaminases play a vital role in:
- Amino Acid Metabolism: They facilitate the conversion of amino acids to keto acids, which can enter metabolic pathways like the citric acid cycle .
- Immune Responses and Pathogen Recognition: Transaminases are involved in the synthesis of amino acids necessary for the production of immune cells and antibodies .
Transaminases operate through a mechanism involving the coenzyme pyridoxal phosphate (PLP). The process can be divided into two half-reactions:
The expression and activity of transaminases are regulated through:
Transaminases have several applications in biomedical research and clinical practice:
Throughout the life cycle, transaminases are involved in:
