Enzymes
Product List
GPT Human
Glutamic-Pyruvate Transaminase Human Recombinant
GPT is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
GPT Human, Active
Glutamic-Pyruvate Transaminase Human Recombinant, Active
The ALT is purified by proprietary chromatographic techniques.
GPT Human, His Active
Glutamic-Pyruvate Transaminase, His Tag Active Human Recombinant
GPT is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
GPT Mouse
Glutamic-Pyruvate Transaminase Mouse Recombinant
GPT Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 519 amino acids (1-496 a.a) and having a molecular mass of 57.5kDa.
GPT is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
GPT Rat
Glutamic-Pyruvate Transaminase Rat Recombinant
GPT2 Human
Glutamic-Pyruvate Transaminase 2 Human Recombinant
GPT2 Human, Active
Glutamic-Pyruvate Transaminase 2 Human Recombinant, Active
GPT2 Mouse
Glutamic-Pyruvate Transaminase 2 Mouse Recombinant
GPT2 Mouse Recombinant produced in E. coli is a single polypeptide chain containing 522 amino acids (1-522) and having a molecular mass of 60.1 kDa. Mouse GPT2 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
GPT2 Mouse, Active
Glutamic-Pyruvate Transaminase 2, Active Mouse Recombinant
GPT2 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 542 amino acids (1-522 aa) and having a molecular mass of 60.1kDa.
GPT2 is fused to a 20 amino acid His tag at N-terminus and purified by proprietary chromatographic techniques.
Escherichia Coli.
Introduction
Transaminases, also known as aminotransferases, are enzymes that catalyze the transfer of an amino group from an amino acid to a keto acid. This process is known as transamination. Transaminases are crucial for the synthesis of amino acids, which are the building blocks of proteins . They are classified based on the specific amino/keto acid pairs they act upon. For example, alanine transaminase (ALT) and aspartate transaminase (AST) are two well-known types .
Transaminases play a vital role in:
- Amino Acid Metabolism: They facilitate the conversion of amino acids to keto acids, which can enter metabolic pathways like the citric acid cycle .
- Immune Responses and Pathogen Recognition: Transaminases are involved in the synthesis of amino acids necessary for the production of immune cells and antibodies .
Transaminases operate through a mechanism involving the coenzyme pyridoxal phosphate (PLP). The process can be divided into two half-reactions:
The expression and activity of transaminases are regulated through:
Transaminases have several applications in biomedical research and clinical practice:
Throughout the life cycle, transaminases are involved in:
