Hormones
Product List
AGRP Human
Agouti–Related Protein Human Recombinant
The Human Agouti-related protein His-Tagged Fusion Protein, produced in E. coli, is 14.4 kDa (calculated) protein containing 112 amino acid residues of the human AGRP and 16 additional amino acid residues - His Tag, thrombin cleavage site (highlighted).
The AGRP is purified by proprietary chromatographic techniques.
BPC-157
BPC-157 Pentadecapeptide
BPC-157 Synthetic is a single, non-glycosylated polypeptide chain containing 15 amino acids, having a molecular mass of 1419.55 Dalton and a Molecular formula of C62H98N16O22.
Sterile Filtered White lyophilized (freeze-dried) powder.
Bremelanotide
Bremelanotide
Bremelanotide Synthetic is a single, non-glycosylated polypeptide chain containing 6 amino acids, having a molecular mass of 1025.16 Dalton and a Molecular formula of C50H68N40O10.
Calcitonin Salmon
Calcitonin Acetate Salmon
C-Peptide
C-Peptide
C-Peptide Synthetic is a single, non-glycosylated polypeptide chain containing 31 amino acids, having a molecular mass of 3020 Dalton and a Molecular formula of C129H211N35O48S .
CRHBP (22-322), Human
Corticotropin Releasing Hormone Binding Protein (22-322 a.a.) Human Recombinant
CRHBP Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 324 amino acids (22-322 a.a) and having a molecular mass of 36.1kDa.
CRHBP is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Escherichia Coli.
CRHBP Human
Corticotropin Releasing Hormone Binding Protein Human Recombinant
CRHBP is purified by proprietary chromatographic techniques.
LL-37
LL-37
LL-37 Synthetic is a single, non-glycosylated polypeptide chain containing 37 amino acids, having a molecular mass of 4493 Dalton and a Molecular formula of C205H340N60O53.
Sterile Filtered White lyophilized (freeze-dried) powder.
MG Human
Menopausal Gonadotropin Human
The MG is purified by proprietary chromatographic techniques.
MOTS-C
MOTS-C
MOTS-C Synthetic is a single, non-glycosylated polypeptide chain containing 16 amino acids, having a molecular mass of 2174.59 Dalton and a Molecular formula of C10H152N280O22 S2.
Sterile Filtered White lyophilized (freeze-dried) powder.
Introduction
Hormones are chemical messengers produced by glands in the endocrine system. They travel through the bloodstream to target organs and tissues, where they regulate various physiological processes. Hormones can be classified into three main categories based on their chemical composition:
Key Biological Properties: Hormones have low molecular weight, act in low concentrations, and are soluble in water, allowing them to be transported via blood . They are not stored beforehand and are secreted in response to specific stimuli.
Expression Patterns and Tissue Distribution: Hormones are produced by various glands, including the pituitary, thyroid, adrenal glands, and pancreas. Each gland produces specific hormones that target different tissues and organs .
Mechanisms with Other Molecules and Cells: Hormones interact with specific receptors on target cells. These interactions can be categorized into two types:
- Lipid-Soluble Hormones: These hormones diffuse through the plasma membrane and bind to intracellular receptors, altering gene expression .
- Water-Soluble Hormones: These hormones bind to cell-surface receptors, initiating intracellular signaling cascades .
Binding Partners and Downstream Signaling Cascades: Hormone-receptor binding triggers a series of events inside the cell, including protein synthesis, enzyme activation or deactivation, and changes in cell permeability .
Control of Expression and Activity: Hormone levels are regulated by feedback mechanisms. Negative feedback loops maintain hormone concentrations within a narrow range, while positive feedback loops amplify hormone production in response to specific stimuli .
Transcriptional Regulation and Post-Translational Modifications: Hormones can influence gene expression by binding to DNA and regulating transcription. Post-translational modifications, such as phosphorylation, can also modulate hormone activity .
Biomedical Research: Hormones are used to study various physiological processes and disease mechanisms. For example, insulin is crucial in diabetes research .
Diagnostic Tools: Hormone levels are measured to diagnose endocrine disorders, such as hypothyroidism and diabetes .
Therapeutic Strategies: Hormone replacement therapies are used to treat conditions like hypothyroidism, menopause, and growth hormone deficiencies .
Development to Aging and Disease: Hormones play a vital role throughout the life cycle. During development, they regulate growth and differentiation. In adulthood, they maintain homeostasis and reproductive functions. As individuals age, hormone levels decline, contributing to age-related changes and diseases .
