Atosiban

Atosiban

Atosiban also called ADH (Anti-Diuretic Hormone) has a molecular formula of C43H67N11O12S2, 3-Mercaptopropionyl-D-Tyr(ET)-Ile-Thr-Asn-Cys-Pro-Orn-Gly-NH2 having a Mw of 994.2 Dalton.

Shipped with Ice Packs
Cat. No.
BT15672
Source
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.

Buserelin

Buserelin

Buserelin contains 9 amino acids Glu-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHEt and having a molecular weight of 1239.44 Dalton.
Shipped with Ice Packs
Cat. No.
BT15763
Source
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.

Cetrorelix

Cetrorelix

Cetrorelix acetate is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity. Cetrorelix acetate is an analog of native GnRH with substitutions of amino acids at positions 1, 2, 3, 6, and 10. The molecular formula is C70H92CIN17O14 (Ac-D-Nal1-D-Cpa2-D-Pal3-Ser4-Tyr5- D-Cit6-Leu7-Arg8-Pro9-D -Ala10-NH2), and the molecular weight is 1431 Dalton, calculated as the anhydrous free base.
Shipped with Ice Packs
Cat. No.
BT15826
Source
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.

DDAVP

Desmopressin

Desmopressin also called ADH (Anti-Diuretic Hormone) has a molecular formula of C46H64N14O12S2 , Mpr-Tyr-Phe-Gln-Asn-Cys-Pro-D-Arg-Gly-NH2 having a Mw of 1069.23 Dalton.
Shipped with Ice Packs
Cat. No.
BT15909
Source
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.

Deslorelin

Deslorelin

Deslorelin is a potent LHRH/GnRH agonist has a molecular formula of C64H83N17O12, pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHC2H having an Mw of 1284.4 Dalton.

Shipped with Ice Packs
Cat. No.
BT15979
Source
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.

Elcatonin

Elcatonin

Elcatonin Synthetic is a single, non-glycosylated polypeptide chain containing 31 amino acids, having a molecular mass of 3363.2 Dalton and a Molecular formula of C148H244N42O47.
Shipped with Ice Packs
Cat. No.
BT16046
Source
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.

Ganirelix

Ganirelix

Ganirelix acetate is a synthetic decapeptide with high antagonistic activity against naturally occurring gonadotropin-releasing hormone (GnRH). Ganirelix acetate is derived from native GnRH with substitutions of amino acids at positions 1, 2, 3, 6, 8, and 10 to form the following molecular formula of the peptide: N-acetyl-3-(2-napthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-N 9 ,N 10 -diethyl- D-homoarginyl-L-leucyl-N 9 ,N 10 -diethyl-L-homoarginyl-L-prolyl-D-alanylamide acetate. The molecular weight for Ganirelix acetate is 1570.4 Dalton as an anhydrous free base.
Shipped with Ice Packs
Cat. No.
BT16124
Source
Appearance
Sterile Filtered colorless liquid formulation.

GHRL Protein

Ghrelin Human

Ghrelin Human contains 28 amino acids and a total molecular mass of 3370.9 Dalton and a molecular formula of C149H249N47O42.
The GHRL is purified by proprietary chromatographic techniques.
Shipped with Ice Packs
Cat. No.
BT16219
Source
Appearance
Sterile Filtered Yellowish lyophilized (freeze-dried) powder that may appear as a gel form.

Goserelin

Goserelin

Goserelin contains 10 amino acids Glu1-His2-Trp3-Ser4-Tyr5-D-Ser(tBu)6-Leu7-Arg8-Pro9-AzGly10-NH2 and having a molecular weight of 1269.43 Dalton.
Shipped with Ice Packs
Cat. No.
BT16264
Source
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.

Hexarelin

Hexarelin

Hexarelin has 7 amino acids H-His-D-2-Methyl-Trp-Ala-Trp-D-Phe-Lys-NH2 and having a molecular weight of 887 Dalton. The Molecular Formula is C47H58N12O6.
Shipped with Ice Packs
Cat. No.
BT16344
Source
Appearance
Sterile Filtered lyophilized (freeze-dried) powder.
Definition and Classification

Peptide hormones are a class of hormones whose molecules are peptides, consisting of short chains of amino acids. They are synthesized in cells from amino acids according to mRNA transcripts, which are synthesized from DNA templates inside the cell nucleus . Peptide hormones can be classified into various types based on their structure and function, including insulin, glucagon, growth hormone, and oxytocin .

Biological Properties

Peptide hormones exhibit several key biological properties:

  • Expression Patterns: They are synthesized in various organs such as the pancreas, hypothalamus, and pituitary gland .
  • Tissue Distribution: Peptide hormones are distributed throughout the body and can be found in insects, all vertebrates, and many other creatures .
  • Key Biological Properties: They have a short half-life, meaning they break apart quickly, allowing organisms to use them to direct processes efficiently .
Biological Functions

Peptide hormones play crucial roles in various biological functions:

  • Primary Biological Functions: They regulate metabolism, growth, and reproduction . For example, insulin regulates blood glucose levels, while growth hormone stimulates growth and cell reproduction .
  • Role in Immune Responses and Pathogen Recognition: Peptide hormones are involved in immune responses and pathogen recognition by interacting with immune cells and modulating their activity .
Modes of Action

Peptide hormones interact with other molecules and cells through specific mechanisms:

  • Binding Partners: They bind to specific receptors on the surface of target cells .
  • Downstream Signaling Cascades: Upon binding to their receptors, peptide hormones trigger intracellular signaling pathways that lead to various cellular responses . For example, the binding of insulin to its receptor activates a signaling cascade that promotes glucose uptake by cells .
Regulatory Mechanisms

The expression and activity of peptide hormones are controlled by various regulatory mechanisms:

  • Transcriptional Regulation: The synthesis of peptide hormones involves gene transcription into precursor nuclear RNA, followed by post-transcriptional modifications .
  • Post-Translational Modifications: Peptide hormones undergo post-translational modifications, such as glycosylation, which are essential for their proper function . Additionally, the regulation of peptide hormones involves releasing factors and secretagogues, primarily through interactions between the hypothalamus and the pituitary gland .
Applications

Peptide hormones have numerous applications in biomedical research, diagnostics, and therapeutics:

  • Biomedical Research: They are used to study cellular communication and hormone regulation .
  • Diagnostic Tools: Peptide hormones serve as biomarkers for various diseases, aiding in diagnosis .
  • Therapeutic Strategies: Peptide hormones are utilized in treatments for conditions such as diabetes (insulin therapy) and growth deficiencies (growth hormone therapy) .
Role in the Life Cycle

Peptide hormones play vital roles throughout the life cycle, from development to aging and disease:

  • Development: They are essential for growth and development, regulating processes such as cell proliferation and differentiation .
  • Aging and Disease: Peptide hormones continue to influence physiological processes in adulthood and are involved in the regulation of metabolism, stress responses, and immune function . Dysregulation of peptide hormones can lead to various diseases, including diabetes and growth disorders .
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