LY6C/G Antibody, Biotin

LY6C/G, also known as Gr-1, is a glycosylphosphatidylinositol (GPI)-anchored protein that belongs to the Ly6 family of proteins. These proteins are primarily expressed on myeloid lineage cells, including neutrophils, monocytes, and macrophages . The LY6C/G antigen is commonly used as a marker for these cell types in various immunological studies.

The LY6C/G protein is a member of the Ly6 family, which is characterized by the presence of a conserved LU domain and a GPI anchor that attaches the protein to the cell surface . The Ly6 family proteins play crucial roles in cell signaling and adhesion. LY6C/G is specifically expressed on neutrophils and other myeloid cells, making it a valuable marker for identifying and studying these cells .

The rat anti-mouse antibody is a secondary antibody that is used to detect mouse primary antibodies in various immunoassays. This antibody is conjugated with biotin, which allows for easy detection using streptavidin-conjugated enzymes or fluorophores . The rat anti-mouse antibody reacts with the heavy and light chains of mouse immunoglobulins, ensuring minimal cross-reactivity with other species .

The LY6C/G, rat anti-mouse antibody, biotin-conjugated, is widely used in immunological research for:

• Flow Cytometry: To identify and quantify LY6C/G-expressing cells in a mixed cell population.
• Immunohistochemistry: To visualize LY6C/G-expressing cells in tissue sections.
• Western Blotting: To detect LY6C/G protein in cell lysates.
• ELISA: To quantify LY6C/G protein levels in biological samples .