HIV1 p24 Antibody, C-91
Sterile Filtered White lyophilized (freeze-dried) powder.
Description
Product Specs
The antibody appears as a sterile-filtered, white powder that has been freeze-dried (lyophilized).
The antibody has been freeze-dried in a solution containing phosphate-buffered saline (PBS).
The antibody is shipped at ambient temperature in its lyophilized (freeze-dried) form.
For long-term storage, keep the lyophilized antibody at 4°C in a dry environment. After reconstituting the antibody, it can be stored at -20°C for up to a month. If not intended for use within a month, it's recommended to divide the reconstituted antibody into smaller portions (aliquots) before freezing.
To reconstitute the lyophilized antibody, add 1 ml of 1x PBS (phosphate-buffered saline) to the vial. Mix gently by swirling, ensuring the solution makes contact with the sides of the vial. Allow 30-60 seconds for the antibody to dissolve completely before use.
Protein A / S-Sepharose.
Mouse Monoclonal antibodies against HIV-1 full length recombinant p24. Captures the p24 antigen. May be paired with mAbs catalog numbers ant-748.
91.
r.HIV-1p24 Core.
mouse IgG1.
Product Science Overview
HIV-1 p24 is a capsid protein that constitutes the core of the Human Immunodeficiency Virus type 1 (HIV-1). It is produced by the digestion of its precursor, Gag p55, by HIV-1 protease . The p24 protein is indispensable for the reproduction of the AIDS virus and is an essential element for the construction of the virus particle .
HIV-1 p24 is detectable from the early stages of HIV infection and is used as a marker for monitoring the progression of the disease and the effectiveness of treatment . The presence of p24 in the blood indicates the amount of virus present, making it a crucial target for diagnostic and therapeutic research .
Mouse antibodies against HIV-1 p24, such as Clone-91, are monoclonal antibodies specifically developed to target the p24 protein. These antibodies are produced by immunizing mice with the HIV-1 p24 antigen and then isolating the specific antibody-producing cells. The cells are fused with myeloma cells to create hybridomas, which can be cultured to produce large quantities of the monoclonal antibody.
The HIV-1 p24 (Mouse Antibody, Clone-91) can be used in various scientific applications, including:
- Western Blotting (WB): To detect the presence of HIV-1 p24 protein in samples.
- Enzyme-Linked Immunosorbent Assay (ELISA): For quantifying the amount of p24 protein.
- Immunocytochemistry (ICC): To visualize the localization of p24 protein within cells.
- Immunohistochemistry (IHC): To detect p24 protein in tissue samples.
These applications are essential for research in understanding the biology of HIV-1, developing diagnostic tools, and evaluating the efficacy of potential treatments.
