Sterile Filtered clear solution.
Greater than 95% as determined by SDS-PAGE.
Thyroid Peroxidase Human Recombinant produced in SF9 is a Biotinylated, glycosylated, polypeptide chain containing 834 amino acids and having a molecular mass of 93 kDa (excluding glycosylation).
The TPO is expressed with a -6xHis tag at C-terminus and purified by proprietary chromatographic techniques.
Human recombinant TPO, particularly the biotinylated form, is produced using recombinant DNA technology. This involves the expression of the TPO gene in suitable host cells, such as Sf9 insect cells . The biotinylation of TPO allows for easy detection and purification using streptavidin-based methods. The recombinant TPO is typically a glycosylated polypeptide chain containing 834 amino acids and has a molecular mass of approximately 93 kDa (excluding glycosylation) .