Norovirus Group-II Paired Antibody
Greater than 90%.
Description
Please note that when ordering for example: 100µg antibody we ship 50µg from each of the antibodies (100µg in total).
Product Specs
Order quantities reflect the total antibody amount; for instance, a 100µg order includes 50µg of each antibody.
Exceeds 90%.
* The Norovirus Group II conjugating antibody is supplied in a solution of 1xPBS with a pH of 7.4.
For long-term storage, adding a carrier protein like 0.1% HSA or BSA is recommended.
Avoid repeated freeze-thaw cycles.
This product is suitable for use in lateral flow immunoassays.
Purified monoclonal IgG by protein A chromatography.
Product Science Overview
Noroviruses are a group of viruses that cause gastroenteritis, an illness characterized by symptoms such as abdominal pain, diarrhea, vomiting, and nausea. These viruses are highly contagious and can spread through contaminated food, water, surfaces, or direct person-to-person contact. Noroviruses are categorized into two main groups: Group I and Group II. Group II noroviruses are particularly significant due to their widespread impact on public health.
Norovirus Group-II is responsible for a substantial number of gastroenteritis cases worldwide. In the United States alone, noroviruses cause approximately 20 million cases of gastroenteritis annually, resulting in around 800 deaths. Globally, noroviruses infect about 267 million people and cause over 200,000 deaths each year. While the illness is generally self-limiting and resolves within a few days, it can be severe and even fatal in very young children, the elderly, immunocompromised individuals, and people in less developed countries.
The Mouse Anti Norovirus Group-II Paired Antibody is a monoclonal antibody developed specifically to detect Norovirus Group-II antigens. This antibody is used in various laboratory research applications, particularly in the development of diagnostic tests for norovirus infections.
Characteristics and Composition
- Type: Monoclonal antibody
- Host: Mouse
- Purity: Greater than 90%, purified by protein A chromatography
- Formulation: The antibody is provided in two vials of sterile filtered clear colorless solution. The capture antibody is in 1xPBS, pH 7.4, and the conjugating antibody is also in 1xPBS, pH 7.4.
Function and Application
The Mouse Anti Norovirus Group-II Paired Antibody consists of two components: the capture antibody and the conjugating antibody. These antibodies target the viral nuclear protein of Norovirus Group-II. The capture antibody is used as a coating antibody, while the conjugating antibody is used to bind to colloid gold. This pairing is essential for the detection of Norovirus Group-II antigens in stool samples through rapid tests, such as lateral flow immunoassays .
Storage and Stability
The antibody is stable at 4°C for one week but should be stored below -18°C for long-term storage. To enhance stability, it is recommended to add a carrier protein, such as 0.1% human serum albumin (HSA) or bovine serum albumin (BSA). It is crucial to avoid freeze-thaw cycles to maintain the antibody’s integrity .
