HSA Fatty Acid free
Sterile Filtered clear yellowish solution.
Greater than 97% as determined by SDS-PAGE.
Description
Product Specs
Product Science Overview
Recombinant Human Serum Albumin (rHSA) is a genetically engineered form of HSA. It is produced using recombinant DNA technology, which involves inserting the human albumin gene into a host organism, such as yeast, bacteria, or plant cells, to produce albumin. This method ensures a high level of purity and consistency, free from potential contaminants and impurities that can be present in plasma-derived HSA .
Fatty Acid Free Human Serum Albumin is a specialized form of HSA that has been processed to remove fatty acids. This is particularly important for certain applications where the presence of fatty acids can interfere with experimental results or therapeutic outcomes. Fatty acid-free HSA is often used in cell culture studies, drug formulation, and other biochemical applications where control over specific fatty acid content is crucial .
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Carrier Protein: HSA functions as a carrier protein for various endogenous and exogenous substances, including fatty acids, hormones, and drugs. It plays a significant role in the pharmacokinetics of many drugs by binding to them and affecting their distribution, metabolism, and excretion .
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Cell Culture: In cell culture studies, fatty acid-free HSA is used to control the specific fatty acid content, which is essential for the growth and maintenance of certain cell lines. This ensures that the cells are exposed to a consistent and controlled environment, leading to more reliable experimental results .
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Therapeutic Uses: rHSA is used in various therapeutic applications, including as a blood volume expander in patients with hypovolemia, as a stabilizer in vaccines and other biologics, and in the treatment of burns and shock .
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Research and Diagnostics: Fatty acid-free HSA is widely used in research and diagnostic applications, such as immunoassays and immunodetection procedures, where it serves as a blocking agent or a carrier protein for the dilution of antibodies .
- Purity and Safety: Recombinant HSA is free from the potential contaminants and impurities that can be present in plasma-derived HSA, such as viruses and prions. This makes it a safer alternative for therapeutic and research applications .
- Consistency: The recombinant production process ensures a high level of consistency and reproducibility, which is essential for reliable experimental results and therapeutic outcomes .
- Ethical Considerations: The use of recombinant technology reduces the reliance on human plasma donations, addressing ethical concerns related to the sourcing of biological materials .
