GH1, GH, GHN, GH-N, hGH-N,Pituitary GH, GH 1.
GH Denis Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 190 amino acids and having a molecular mass of 21810 Dalton.
GH is purified by proprietary chromatographic techniques.
GH1, GH, GHN, GH-N, hGH-N,Pituitary GH, GH 1.
Growth hormone (GH) is a member of the prolactin family of hormones, which play a crucial role in growth control. The gene responsible for GH, along with four other related genes, is located at the GH locus on chromosome 17. These genes share a high degree of sequence identity, and alternative splicing generates additional isoforms, leading to further diversity and specialization. GH Denis Recombinant is expressed in the pituitary gland but not in placental tissue, unlike the other genes in the GH locus .
GH Denis Recombinant is produced in Escherichia coli (E. coli) bacteria. The production process involves inserting the gene encoding the human growth hormone into the bacterial DNA. The bacteria then use this genetic information to produce the GH protein. The resulting protein is a single, non-glycosylated polypeptide chain containing 190 amino acids and has a molecular mass of 21,810 Daltons .
The protein is purified using proprietary chromatographic techniques to ensure high purity and quality. The final product is a sterile, filtered, white lyophilized (freeze-dried) powder .
Lyophilized GH Denis Recombinant is stable at room temperature for up to three weeks. However, for long-term storage, it should be kept desiccated below -18°C. Upon reconstitution, the protein should be stored at 4°C for short-term use (2-7 days) and below -18°C for long-term use. It is recommended to add a carrier protein, such as 0.1% human serum albumin (HSA) or bovine serum albumin (BSA), to prevent freeze-thaw cycles .