NME2 Antibody
Nucleoside diphosphate kinase B, NDPK-B, NDPKB, NM23-H2, NM23B, EC 2.7.4.6, NDP kinase B, C-myc purine-binding transcription factor PUF, NDK B, NME2, puf, MGC111212.
Description
Product Specs
Nucleoside diphosphate kinase B, NDPK-B, NDPKB, NM23-H2, NM23B, EC 2.7.4.6, NDP kinase B, C-myc purine-binding transcription factor PUF, NDK B, NME2, puf, MGC111212.
NME2 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
PAT5F4AT.
Anti-human NME2 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human NME2 amino acids 1-152 purified from E. coli.
Mouse IgG2b heavy chain and κ light chain.
Product Science Overview
Non-metastatic cells are a crucial area of study in cancer research, as they provide insights into the mechanisms that prevent cancer cells from spreading to other parts of the body. The term “Non-Metastatic Cells 2, Mouse Anti Human” refers to a specific type of non-metastatic cell line used in research, particularly in the context of studying human cancers in mouse models.
Non-metastatic cells are cancer cells that do not have the ability to spread from the primary tumor site to other parts of the body. These cells are contrasted with metastatic cells, which can invade other tissues and form secondary tumors. Understanding the differences between metastatic and non-metastatic cells is essential for developing targeted cancer therapies.
Mouse models are extensively used in cancer research due to their genetic, biological, and behavioral similarities to humans. These models allow researchers to study the progression of cancer and the effectiveness of potential treatments in a controlled environment. Non-metastatic cell lines, such as “Non-Metastatic Cells 2,” are often used in these models to investigate the factors that prevent metastasis.
Mouse anti human antibodies are antibodies produced in mice that are specific to human antigens. These antibodies are valuable tools in biomedical research, including cancer research, as they can be used to detect and quantify human proteins in various experimental settings. In the context of non-metastatic cells, mouse anti human antibodies can help identify and study specific proteins that may play a role in preventing metastasis.
The study of non-metastatic cells using mouse models and mouse anti human antibodies has several important applications:
- Identifying Metastasis Suppressors: Researchers can use these tools to identify proteins and genes that suppress metastasis, providing potential targets for new cancer therapies.
- Understanding Tumor Microenvironment: Non-metastatic cells can help researchers understand how the tumor microenvironment influences cancer progression and metastasis.
- Drug Testing: Mouse models with non-metastatic cells can be used to test the efficacy of new drugs in preventing metastasis.
