LTF Apo Human

Lactoferrin Apo, also known as Apolactoferrin, is a form of lactoferrin that is devoid of iron. Lactoferrin itself is a multifunctional glycoprotein found in various secretory fluids, including milk, saliva, tears, and nasal secretions. It plays a crucial role in the immune system, exhibiting antibacterial, antiviral, antifungal, and anti-inflammatory properties .

Lactoferrin was first isolated from human milk by scientist Johanson Bengt in 1960 . It is composed of 703 amino acids and has a molecular weight of approximately 80 kDa . The protein consists of two lobes, each capable of binding one iron ion, which is essential for its biological functions .

Lactoferrin’s primary function is to bind and transport iron, which is vital for various physiological processes. By sequestering iron, lactoferrin limits the availability of this essential nutrient to pathogenic microorganisms, thereby inhibiting their growth . Additionally, lactoferrin interacts with cellular receptors, modulating immune responses and promoting the growth of beneficial bacteria in the gut .

Recombinant human lactoferrin is produced using genetic engineering techniques. The gene encoding human lactoferrin is inserted into host cells, such as bacteria, yeast, or mammalian cells, which then express the protein. This method allows for large-scale production of lactoferrin with similar biological activity to the natural protein .

Lactoferrin Apo has numerous applications in healthcare and biotechnology. It is used in dietary supplements, infant formula, and functional foods due to its immune-boosting properties . Additionally, lactoferrin is explored as a potential therapeutic agent for various conditions, including infections, inflammation, and cancer .