KCTD15 PAT2B11AT Antibody

Clone PAT2B11AT is a mouse monoclonal antibody specifically designed to target the KCTD15 protein in humans . Monoclonal antibodies are laboratory-produced molecules engineered to serve as substitute antibodies that can restore, enhance, or mimic the immune system’s attack on cells.

Applications

The PAT2B11AT clone is widely used in various research applications, including:

• ELISA (Enzyme-Linked Immunosorbent Assay): This technique is used to detect and quantify soluble substances such as proteins, peptides, antibodies, and hormones.
• Western Blot (WB): This method is used to detect specific proteins in a sample by using antibody binding.
• Flow Cytometry (FC/FACS): This technique is used to analyze the physical and chemical characteristics of particles in a fluid as it passes through at least one laser.
• Immunocytochemistry (ICC): This method is used to detect the presence and localization of proteins within individual cells.
• Immunofluorescence (IF): This technique uses antibodies labeled with fluorescent dyes to detect specific proteins in cells or tissue sections .

Mouse anti-human antibodies are antibodies produced in mice that are specific to human antigens. These antibodies are commonly used in research and diagnostic applications due to their high specificity and affinity for human proteins . They are essential tools in various immunological assays and have significantly contributed to advancements in biomedical research.

Human Anti-Mouse Antibody (HAMA) Response

One potential issue with using mouse anti-human antibodies is the Human Anti-Mouse Antibody (HAMA) response. This response occurs when the human immune system recognizes the mouse antibodies as foreign and mounts an immune response against them. The HAMA response can range from mild reactions, such as rashes, to severe and life-threatening conditions like kidney failure .