Influenza-A Paired Antibody
Greater than 90%.
Description
Product Specs
Purified monoclonal IgG by protein A chromatography.
Product Science Overview
Influenza A virus is a significant cause of morbidity and mortality worldwide. The virus undergoes frequent antigenic changes, making it challenging to develop effective vaccines and treatments. Mouse anti-Influenza-A paired antibodies are crucial tools in influenza research, particularly for studying the virus’s behavior, immune response, and vaccine efficacy.
Influenza A virus is an RNA virus belonging to the Orthomyxoviridae family. It is characterized by its surface glycoproteins, hemagglutinin (HA) and neuraminidase (NA), which are essential for the virus’s ability to infect host cells and spread. The virus is known for its high mutation rate, leading to the emergence of new strains and necessitating continuous monitoring and vaccine updates.
Mouse models are widely used in influenza research due to their genetic similarity to humans and their ability to mimic human disease. These models help researchers understand the virus’s pathogenesis, immune response, and the efficacy of vaccines and antiviral drugs. Mice can be infected with various strains of Influenza A virus, allowing for the study of different aspects of the virus and its interaction with the host immune system .
Anti-Influenza-A paired antibodies are generated by immunizing mice with specific influenza antigens. These antibodies are then harvested and purified for use in various assays and experiments. The paired antibodies typically consist of a primary antibody that binds to a specific viral antigen and a secondary antibody that recognizes the primary antibody, often conjugated with a detectable marker such as an enzyme or fluorophore.
- Diagnostic Assays: These antibodies are used in diagnostic assays such as ELISA (enzyme-linked immunosorbent assay) and Western blot to detect the presence of influenza antigens in clinical samples.
- Vaccine Development: Mouse anti-Influenza-A paired antibodies are used to evaluate the efficacy of new vaccines by measuring the immune response in vaccinated animals.
- Research Studies: These antibodies help researchers study the virus’s behavior, immune evasion mechanisms, and the host’s immune response to infection .
