HOXC11 Human
Homeobox C11 Human Recombinant
Cat. No.
BT22011
Source
Escherichia Coli.
Synonyms
Homeobox protein Hox-C11, Homeobox protein Hox-3H, HOXC11,
HOX3H.
Appearance
Sterile Filtered clear solution.
Purity
Greater than 80.0% as determined by SDS-PAGE.
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Shipped with Ice Packs 
In Stock 
Description
HOXC11 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 327 amino acids (1-304 a.a.) and
having a molecular mass of 36.1kDa. HOXC11 is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Product Specs
Introduction
Homeobox C11 (HOXC11) is a member of the Abd-B homeobox family. This family of transcription factors, encoded for by homeobox genes, are well conserved and play a vital role in morphogenesis in all multicellular organisms. HOXC11 is one of numerous homeobox HOXC genes placed in a cluster on chromosome 12. It attaches to a promoter element of lactase-phlorizin hydrolase and also takes part in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been defined however, its full-length nature has not been determined.
Description
HOXC11 Human Recombinant, produced in E.Coli, is a single, non-glycosylated polypeptide chain containing 327 amino acids (1-304 a.a.) and having a molecular mass of 36.1kDa. HOXC11 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Physical Appearance
Sterile Filtered clear solution.
Formulation
HOXC11 protein solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M UREA and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 80.0% as determined by SDS-PAGE.
Synonyms
Homeobox protein Hox-C11, Homeobox protein Hox-3H, HOXC11,
HOX3H.
Source
Escherichia Coli.
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MGSMFNSVNL GNFCSPSRKE RGADFGERGS CASNLYLPSC TYYMPEFSTV
SSFLPQAPSR QISYPYSAQV PPVREVSYGL EPSGKWHHRN SYSSCYAAAD ELMHRECLPP STVTEILMKN
EGSYGGHHHP SAPHATPAGF YSSVNKNSVL PQAFDRFFDN
AYCGGGDPPA EPPCSGKGEA KGEPEAPPAS GLASRAEAGA EAEAEEENTN
PSSSGSAHSV AKEPAKGAAP NAPRTRKKRC PYSKFQIREL EREFFFNVYI NKEKRLQLSR MLNLTDRQVK
IWFQNRRMKE KKLSRDRLQY FSGNPLL.
Product Science Overview
Gene and Protein Structure
The HOXC11 gene is one of several homeobox HOXC genes located in a cluster on chromosome 12 in humans . The gene encodes a protein that is involved in the regulation of gene expression, particularly during early development. The recombinant HOXC11 protein is typically produced in E. coli and is a single, non-glycosylated polypeptide chain containing 327 amino acids, with a molecular mass of approximately 36.1 kDa .
Function and Role
Expression and Localization
Structural Insights
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