Dengue 3 NS1 Antibody
Rabbit.
Description
The polyclonal antibody to dengue serotype 3 NS1 was collected from the rabbit immunized with full length recombinant dengue serotype 3 NS1 antigen, reactive to all dengue serotype NS1.
Product Specs
Rabbit.
Purified by protein A chromatography.
Purified IgG.
Product Science Overview
Dengue virus (DENV) is a member of the Flavivirus family and is responsible for causing dengue fever, a significant mosquito-borne illness affecting millions globally . The virus has four serotypes (DENV-1 to DENV-4), and infection with one serotype does not provide immunity against the others. Among the various proteins encoded by the dengue virus, the non-structural protein 1 (NS1) is particularly noteworthy. NS1 is a highly conserved glycoprotein found in all flaviviruses and plays a crucial role in viral replication .
NS1 is secreted by infected cells and can be detected in the blood of patients during the early stages of dengue infection. Its presence in the bloodstream makes it an excellent marker for early diagnosis of dengue. Commercially available diagnostic kits, such as ELISA, utilize NS1 to detect dengue infections .
Polyclonal antibodies are a mixture of antibodies produced by different B cell clones in the body. They are capable of recognizing and binding to multiple epitopes on a single antigen. Polyclonal antibodies are typically produced by immunizing animals, such as rabbits, with an antigen of interest. The immune response generated in the animal leads to the production of antibodies, which are then harvested from the animal’s serum .
Polyclonal Rabbit Anti-Dengue 3 NS1 antibodies are specifically raised against the NS1 protein of the Dengue virus serotype 3 (DENV-3). These antibodies are produced by immunizing rabbits with the full-length NS1 protein of DENV-3. The resulting antibodies are then purified and can be used in various applications, including Western Blotting and ELISA .
The primary application of Polyclonal Rabbit Anti-Dengue 3 NS1 antibodies is in the detection and study of dengue virus infections. These antibodies are highly specific and sensitive, making them valuable tools for research and diagnostic purposes. They can be used to detect the presence of NS1 in patient samples, helping in the early diagnosis of dengue. Additionally, they are useful in studying the biology and pathogenesis of the dengue virus .
