Dengue 2 NS1 Antibody
Protein is >90% pure.
Description
Product Specs
Purified by affinity chromatographic technique.
Product Science Overview
Polyclonal Rabbit Anti-Dengue 2 NS1 antibodies are a crucial tool in the study and diagnosis of dengue virus infections. These antibodies are developed in rabbits and are designed to target the non-structural protein 1 (NS1) of the Dengue virus type 2. The NS1 protein is a highly conserved glycoprotein that plays a significant role in the virus’s replication and pathogenesis.
Dengue virus is a member of the Flaviviridae family and is transmitted to humans primarily through the bite of infected Aedes mosquitoes. There are four serotypes of the dengue virus (DENV-1, DENV-2, DENV-3, and DENV-4), each capable of causing dengue fever and severe dengue hemorrhagic fever. The NS1 protein is a non-structural protein that is secreted by infected cells and is involved in immune evasion and viral replication.
Polyclonal antibodies are produced by immunizing animals, such as rabbits, with an antigen—in this case, the Dengue virus type 2 NS1 protein. The immune system of the rabbit generates a diverse array of antibodies that recognize multiple epitopes on the NS1 protein. These antibodies are then harvested from the rabbit’s serum and purified for use in various applications.
Polyclonal Rabbit Anti-Dengue 2 NS1 antibodies are used in a variety of scientific and diagnostic applications, including:
- Western Blotting: To detect the presence of NS1 protein in samples.
- Immunocytochemistry (ICC): To visualize the localization of NS1 protein within cells.
- Enzyme-Linked Immunosorbent Assay (ELISA): To quantify the amount of NS1 protein in samples.
- Flow Cytometry: To analyze the expression of NS1 protein on the surface of cells.
- Immunohistochemistry (IHC): To detect NS1 protein in tissue sections.
The detection of NS1 protein is critical for the early diagnosis of dengue virus infections. NS1 is present in the blood of infected individuals during the early stages of infection, making it a valuable biomarker for early detection. Polyclonal Rabbit Anti-Dengue 2 NS1 antibodies are also used in research to study the pathogenesis of dengue virus and to develop vaccines and therapeutic strategies.
