Collagen-I Goat

Goat Collagen-I
Cat. No.
BT12284
Source

Goat tissues.

Synonyms
Appearance

Filtered White lyophilized (freeze-dried) powder.

Purity

 Greater than 90.0% as determined by SDS-PAGE 90.0%.

Usage
THE BioTek's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Shipped with Ice Packs
In Stock

Description

Goat Collagen-I is a natural protein purified from Goat tissues. Collagen-I is purified by proprietary chromatographic techniques.

Product Specs

Introduction

As a critical component of the extracellular matrix, collagen provides structural support and tensile strength to tissues. Derived from collagen, gelatin shares similar applications and has been widely used. Although abundant and cost-effective, animal-sourced collagen and gelatin pose potential risks such as inflammatory reactions and contamination. These concerns stem from the inherent variability of animal-derived products and potential exposure to pathogens. Recombinant collagens offer a safer alternative by minimizing these risks while closely resembling native collagen.

Description

This product consists of Collagen-I, a natural protein, extracted from Goat tissues and purified through proprietary chromatographic techniques.

Physical Appearance

It appears as a white, lyophilized powder after filtration.

Formulation

The lyophilization process of Collagen-I is carried out without any additives.

Solubility

For optimal use, prepare a working stock solution by adding 0.5 M acetic acid, pH 2.5, to achieve a concentration of at least 100 μg/ml. This stock solution can be further diluted in other aqueous solutions as needed.

Stability

Lyophilized Collagen-I remains stable for up to 3 weeks when stored at room temperature. However, for extended storage, it is recommended to store it desiccated below -18°C. After reconstitution, Collagen-I can be stored at 4°C for 2-7 days and below -18°C for longer periods. To ensure long-term stability, adding a carrier protein such as 0.1% HSA or BSA is recommended. Avoid repeated freeze-thaw cycles.

Purity

The purity exceeds 90.0% as determined by SDS-PAGE analysis.

Source

Goat tissues.

Product Science Overview

What is Goat Collagen-I?

Goat Collagen-I is a natural protein purified from goat tissues. It is primarily composed of two α1 (I) chains and one α2 (I) chain . This type of collagen is known for its high purity and is often used in various research applications due to its structural and mechanical properties .

Purification and Applications

Goat Collagen-I is purified using proprietary chromatographic techniques to ensure high purity, typically greater than 90% . The purified collagen is often lyophilized (freeze-dried) without additives to maintain its stability and functionality .

Applications of Goat Collagen-I include:

  • Cell Culture Surface Coatings: Facilitates cell attachment, growth, differentiation, and migration.
  • Tissue Engineering Scaffolds: Provides a structural framework for tissue regeneration.
  • 3D Bioprinting: Used as a bioink for printing complex tissue structures.
  • Cell Functional Assays: Assists in studying cell behavior and function .
Storage and Handling

Lyophilized Goat Collagen-I is stable at room temperature for up to three weeks but should be stored desiccated below -18°C for long-term storage . Upon reconstitution, it should be stored at 4°C for short-term use and below -18°C for long-term use. To prevent degradation, it is recommended to add a carrier protein such as 0.1% HSA or BSA and avoid freeze-thaw cycles .

Importance in Research

Goat Collagen-I is crucial in various research fields due to its ability to mimic the natural ECM environment. It is widely used in studies related to tissue engineering, regenerative medicine, and cell biology. Its high purity and structural properties make it an ideal choice for creating reliable and reproducible experimental conditions .

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