Collagen-I Bovine
Bovine skin.
Filtered White lyophilized (freeze-dried) powder.
> 90.0%.
Description
Bovine Collagen-I is a natural protein purified from bovine skin. Collagen-I is purified by proprietary chromatographic techniques.
Product Specs
Collagen, a key structural protein, provides tensile strength and integrity to tissues. Collagen and its derivative, gelatin, have a long history of use in various fields. While animal-sourced collagen is readily available and cost-effective, it can pose risks such as inflammatory reactions and potential contamination. The inherent variability in animal collagen extraction and its susceptibility to modifications throughout its lifespan contribute to lot-to-lot inconsistencies. Recombinant collagens offer a safer alternative by minimizing inflammation, immune responses, and disease transmission risks associated with animal-derived products.
Bovine Collagen-I is a naturally occurring protein extracted and purified from bovine skin using specialized chromatographic methods.
White, lyophilized powder that has been filtered.
Collagen-I is lyophilized without the addition of any other substances.
To create a working stock solution, add 0.1M acetic acid (pH 3.0) to the lyophilized pellet and allow it to dissolve completely. A concentration of 1-5mg/ml is recommended.
Lyophilized Collagen-I is stable at room temperature for up to 3 weeks. However, it is recommended to store it desiccated at a temperature below -18°C. After reconstitution, store Collagen-I at 4°C for no longer than 2-7 days. For extended storage, freeze at -18°C. It is advisable to add a carrier protein (0.1% HSA or BSA) for long-term storage. Avoid repeated freezing and thawing cycles.
Greater than 90.0% pure.
Bovine skin.
Product Science Overview
Collagen is a protein that forms the primary component of connective tissues in the body, including skin, tendons, ligaments, and bones. It acts as a scaffold, providing strength and structure. There are several types of collagen, with Type I being the most common, accounting for about 90% of the body’s collagen .
- Wound Healing: Bovine Collagen-I is widely used in the medical field for wound healing. It provides a matrix that supports cell growth, differentiation, attachment, and migration, which are essential for effective wound healing .
- Supplements: It is also used as a dietary supplement to support joint, skin, and gut health. Bovine Collagen-I supplements are available in various forms, including powders, capsules, gummies, and functional drinks .
- Tissue Engineering: In tissue engineering, Bovine Collagen-I is used to create scaffolds for culturing primary cells such as keratinocytes and hepatocytes. These scaffolds provide a 3D matrix that mimics the natural extracellular matrix, promoting cell growth and differentiation .
- Skin Health: Bovine Collagen-I helps improve skin elasticity, reduce wrinkles, and increase skin moisture. It is particularly beneficial for aging skin, as collagen production naturally decreases with age .
- Joint Health: It supports joint health by providing the necessary building blocks for cartilage repair and maintenance. This can help reduce joint pain and improve mobility .
- Gut Health: Bovine Collagen-I can also support gut health by strengthening the gut lining and promoting the growth of beneficial gut bacteria .
