C1QTNF4 Human
Description
Product Specs
Product Science Overview
CTRP4, like other CTRPs, has a modular structure that includes:
- N-terminal signal peptide: Directs the protein to the secretory pathway.
- Short variable domain: Contributes to the functional diversity of the protein.
- Collagenous domain: Facilitates the formation of higher-order structures.
- C-terminal globular C1q domain: Responsible for the protein’s biological activity .
CTRP4 is involved in various metabolic processes and has been shown to have anti-inflammatory and insulin-sensitizing properties . It plays a crucial role in maintaining glucose and lipid homeostasis, making it a potential target for therapeutic interventions in metabolic disorders such as obesity, type 2 diabetes, and cardiovascular diseases .
CTRP4 and other members of the CTRP family are secreted proteins that act as adipokines, which are bioactive molecules produced by adipose tissue . These proteins are essential for the regulation of energy metabolism and have been implicated in the pathogenesis of metabolic syndrome, a cluster of conditions that increase the risk of heart disease, stroke, and type 2 diabetes .
The expression of CTRP4 is regulated by various factors, including nutritional status, hormonal signals, and inflammatory mediators . Dysregulation of CTRP4 expression has been associated with metabolic disorders, highlighting its importance in maintaining metabolic health .
Given its role in metabolic regulation, CTRP4 is considered a promising target for the development of new therapies for metabolic diseases . Research has shown that pharmacological interventions and lifestyle modifications can alter the expression of CTRP4, suggesting that it may be possible to modulate its activity to improve metabolic health .
In conclusion, Complement C1q Tumor Necrosis Factor-Related Protein 4 (Human Recombinant) is a vital component of the CTRP family with significant roles in metabolism and inflammation. Its potential as a therapeutic target makes it an exciting area of research for the treatment of metabolic disorders.
