BTC Mouse

Betacellulin is a glycoprotein composed of approximately 80 amino acid residues . It is known for its role as a growth-promoting factor, particularly in the context of pancreatic beta cells . The mature form of Betacellulin is a ligand for the EGF receptor (ErbB-1) and can also interact with other members of the ErbB receptor family, including ErbB-2, ErbB-3, and ErbB-4 .

Betacellulin has been shown to stimulate cell proliferation in various cell types, including fibroblasts and epithelial cells . It plays a significant role in the growth and development of tissues and has been implicated in processes such as wound healing and tissue regeneration .

Recombinant Betacellulin (Mouse) is typically produced using bacterial expression systems, such as Escherichia coli . The recombinant protein is purified to high levels of purity, often exceeding 90% as determined by SDS-PAGE . The endotoxin levels are kept low to ensure the protein’s suitability for biological applications .

Recombinant Betacellulin is used in various research applications, including studies on cell proliferation, tissue regeneration, and receptor signaling pathways . It is also utilized in the development of therapeutic strategies for conditions such as diabetes and wound healing .

Recombinant Betacellulin is typically lyophilized and can be stored at -20°C to -80°C for extended periods . Upon reconstitution, it is recommended to store the protein under sterile conditions to maintain its stability and activity .

Betacellulin’s role as a potent growth factor and its interactions with the EGF receptor family make it a valuable tool in both basic and applied biological research.