H1N1 Beijing

The H1N1 Influenza-A Virus Beijing/262/95 is a strain of the H1N1 subtype of the Influenza A virus. This particular strain was isolated in Beijing, China, in 1995. Influenza A viruses are known for their ability to cause significant respiratory illnesses in humans and animals, and the H1N1 subtype has been responsible for several pandemics throughout history.

The H1N1 influenza virus has a long history, dating back to the 1918 Spanish flu pandemic, which caused millions of deaths worldwide . Over the years, the H1N1 virus has undergone numerous genetic changes, leading to the emergence of various strains. The Beijing/262/95 strain is one of these variants, which has been studied for its unique genetic and antigenic properties .

The H1N1 Influenza-A Virus Beijing/262/95 belongs to the delta-like clade of the swine H1 lineage . Genetic analyses have shown that this strain has distinct genetic markers that differentiate it from other H1N1 strains. The hemagglutinin (HA) protein, which is responsible for the virus’s ability to bind to host cells, has been a focal point of research. The HA protein of the Beijing/262/95 strain has been expressed in various host systems for study and reagent production .

Since its isolation in 1995, the Beijing/262/95 strain has remained geographically restricted to Asia . This limited distribution contrasts with other H1N1 strains, which have spread globally. The reasons for this geographic restriction are not entirely understood but may be related to specific genetic and antigenic properties of the strain.

The H1N1 Influenza-A Virus Beijing/262/95 has been the subject of various research studies aimed at understanding its genetic makeup and potential impact on public health. Researchers have used this strain to study mutation accumulation and the evolutionary dynamics of the H1N1 virus . These studies have provided valuable insights into the mechanisms of viral evolution and the factors that influence the emergence and spread of new influenza strains.