BD 1 Mouse

BD 1 Mouse
Cat. No.
BT13601
Source
Escherichia Coli.
Synonyms
Beta-defensin 1, BD-1, Defensin beta 1, hBD-1, HBD1, HBP1, DEFB1, HBD-1, HBP-1, DEFB101, DEFB-1, MGC51822.
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity
Greater than 97.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Usage
THE BioTek's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Shipped with Ice Packs
In Stock

Description

BD 1 Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 37 amino acids and having a molecular mass of 4.1 KDa.
The BD 1 Mouse is purified by proprietary chromatographic techniques.

Product Specs

Introduction
The Defensin family consists of highly similar antimicrobial and cytotoxic peptides produced by neutrophils. Beta Defensin-1, a member of this family, plays a crucial role in protecting epithelial surfaces from microbial colonization. It exhibits close similarity to Defensin Alpha-1 and has been implicated in the development of cystic fibrosis. Studies have shown that skin affected by atopic dermatitis and mycosis fungoides exhibits reduced expression of human Beta Defensin-1 mRNA but increased expression of human Beta Defensin-2 and -3 mRNA. Notably, epithelial cells are known to express high levels of Beta Defensin. Additionally, Beta-defensin 1 may contribute to the pathogenesis of severe sepsis.
Description
Recombinant Mouse BD 1, produced in E. coli, is a single, non-glycosylated polypeptide chain comprising 37 amino acids. With a molecular weight of 4.1 kDa, it is purified using proprietary chromatographic techniques.
Physical Appearance
Sterile Filtered White lyophilized powder.
Formulation
Lyophilized from a 0.2µm filtered concentrated solution in phosphate-buffered saline (PBS) at pH 7.4.
Solubility
To reconstitute lyophilized Mouse BD-1, it is recommended to dissolve it in sterile 18 MΩ·cm H₂O at a concentration of at least 100 µg/ml. This solution can then be further diluted in other aqueous solutions.
Stability
Lyophilized Mouse BD 1 remains stable at room temperature for up to 3 weeks. However, for long-term storage, it is recommended to store it desiccated at a temperature below -18°C. After reconstitution, BD 1 should be stored at 4°C for 2-7 days. For future use, store it below -18°C. The addition of a carrier protein (0.1% HSA or BSA) is recommended for extended storage. Avoid repeated freeze-thaw cycles.
Purity
The purity of the product exceeds 97.0%, as determined by: (a) Reverse-phase high-performance liquid chromatography (RP-HPLC) analysis. (b) Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) analysis.
Biological Activity
The biological activity is assessed based on the ability to chemoattract CD34+ dendritic cells within a concentration range of 0.1-1.0 µg/ml. This corresponds to a specific activity of 1,000-10,000 units/mg.
Synonyms
Beta-defensin 1, BD-1, Defensin beta 1, hBD-1, HBD1, HBP1, DEFB1, HBD-1, HBP-1, DEFB101, DEFB-1, MGC51822.
Source
Escherichia Coli.
Amino Acid Sequence
DQYKCLQHGG FCLRSSCPSN TKLQGTCKPD KPNCCKS.

Product Science Overview

Introduction

BD-1 is an exploration droid that played a significant role in the events following the fall of the Galactic Republic. This droid is known for its companionship with Jedi Master Eno Cordova and later with Cal Kestis, a former Padawan who survived Order 66.

Background and History

BD-1 was designed as an exploration droid, equipped with various tools and features to assist in archaeological and exploratory missions. During the last years of the Galactic Republic, BD-1 accompanied Jedi Master Eno Cordova on his journey to uncover the history of the Zeffo, an ancient civilization. Cordova, realizing the dangers they faced, programmed BD-1’s memory to be blocked, only to be revealed by someone the droid trusted .

Following the rise of the Galactic Empire and the execution of Order 66, BD-1 remained on the planet Bogano, near the Zeffo Vault. It was here that the droid encountered Cal Kestis, a former Padawan who was on a mission to rebuild the fallen Jedi Order. BD-1 quickly formed a bond with Kestis and became an invaluable companion on his journey .

Characteristics and Features

BD-1 is characterized by its small, compact design, making it highly mobile and versatile. The droid is equipped with a variety of tools, including a spotlight, scomp link, holoprojector, stim canister storage, and electro darts. These features make BD-1 an essential companion for exploration and combat situations .

Role in “Star Wars Jedi: Fallen Order”

In the game “Star Wars Jedi: Fallen Order,” BD-1 plays a crucial role in assisting Cal Kestis on his quest to uncover the secrets of the Zeffo and rebuild the Jedi Order. The droid’s ability to scan artifacts, provide healing stim canisters, and access locked areas through its scomp link proves invaluable throughout the journey. BD-1’s loyalty and resourcefulness make it a beloved character among fans of the game .

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