Treponema p17 16.4kDa

The p17 protein of Treponema pallidum, also known as 17 kDa lipoprotein or TP_0435, is a fragment protein expressed in Escherichia coli. This recombinant protein has a molecular mass of 16.4 kDa and is non-glycosylated . The p17 protein plays a crucial role in the bacterium’s structure and function, contributing to its ability to move in a corkscrew motion through viscous mediums such as mucus .

Recombinant Treponema pallidum p17 protein is produced in Escherichia coli and is typically purified to greater than 90% purity . The protein is suitable for various applications, including ELISA (enzyme-linked immunosorbent assay) and Western Blot (WB) analysis . The recombinant protein is often fused to a His tag at the N-terminus to facilitate purification .

The recombinant p17 protein is widely used in research for studying the pathogenesis of Treponema pallidum and developing diagnostic tools for syphilis. Its high purity and specific expression make it an ideal candidate for use in ELISA and WB assays .

The recombinant p17 protein is stable at room temperature for up to four weeks but should be stored below -18°C to maintain its integrity. It is recommended to avoid freeze-thaw cycles to prevent degradation .