SSR4 Antibody
Description
Product Specs
Product Science Overview
Signal sequence receptor delta, also known as translocon-associated protein delta, is a subunit of the translocon-associated protein complex. This complex plays a crucial role in the translocation of proteins across the endoplasmic reticulum membrane. The receptor is encoded by the SSR4 gene, which is located on the Xq28 region of the human genome .
The SSR4 gene consists of six exons and is approximately 70 kilobases telomeric to the adrenoleukodystrophy gene. The gene is arranged in a compact head-to-head manner with the isocitrate dehydrogenase 3 gamma gene, and both genes are driven by a bidirectional promoter located between them. This promoter initiates the transcription of both genes, which are involved in unrelated biochemical pathways and are located in different compartments of the cell .
The primary function of the signal sequence receptor delta is to facilitate the translocation of newly synthesized proteins across the endoplasmic reticulum membrane. This process is essential for protein secretion and proper cellular function. The receptor is part of a larger complex that includes other subunits, each playing a specific role in the translocation process .
The mouse anti human signal sequence receptor delta antibody is a monoclonal antibody produced by immunizing mice with recombinant human signal sequence receptor delta protein. This antibody is used in various research applications, including Western blotting, enzyme-linked immunosorbent assay, and immunocytochemistry. It is highly specific and binds to the human signal sequence receptor delta protein, allowing researchers to study its expression and function in different biological contexts .
The mouse anti human signal sequence receptor delta antibody has been widely used in research to study protein translocation and secretion. It has also been employed in the investigation of diseases related to protein misfolding and secretion defects. By understanding the role of signal sequence receptor delta in these processes, researchers can develop new therapeutic strategies for treating related disorders .
