RPL26L1 Human

Ribosomal Protein L26-Like 1, also known as RPL26L1, is a protein that belongs to the ribosomal protein family. This protein is involved in the process of protein synthesis within the cell. It is a component of the 60S ribosomal subunit, which plays a crucial role in translating messenger RNA (mRNA) into functional proteins .

The RPL26L1 gene encodes the Ribosomal Protein L26-Like 1. This gene shares high sequence similarity with the ribosomal protein L26 gene. The protein encoded by RPL26L1 is located in the cytoplasm and is involved in the structural constitution of ribosomes . The gene undergoes alternative splicing, resulting in multiple transcript variants that encode the same protein .

RPL26L1 is primarily involved in the translation process, where it contributes to the assembly and function of the ribosome. The ribosome is responsible for synthesizing proteins by translating the genetic code carried by mRNA. RPL26L1, as part of the 60S ribosomal subunit, plays a structural role in maintaining the integrity and function of the ribosome .

Recombinant Human RPL26L1 is a form of the protein that is produced through recombinant DNA technology. This involves inserting the gene encoding RPL26L1 into a suitable expression system, such as Escherichia coli (E. coli), to produce the protein in large quantities. The recombinant protein is often tagged with a His-tag at the N-terminus to facilitate purification using conventional chromatography techniques .

Recombinant Human RPL26L1 is used in various research applications, including studies on protein synthesis, ribosome function, and the role of ribosomal proteins in cellular processes. It is also used in structural biology to understand the architecture of ribosomes and their components .