Introduction
PARK7 is a ubiquitously expressed protein with roles in various cellular processes, including spermatogenesis, fertilization, cancer, RNA-binding, androgen-receptor signaling, and oxidative stress. Mutations in PARK7 are linked to autosomal recessive early-onset Parkinson's disease 7 (Park7).
Physical Appearance
A colorless solution that has been sterilized by filtration.
Formulation
The solution contains 1mg/ml of PARK7 P1E12AT Antibody in a buffer of PBS at pH 7.4, with 10% Glycerol and 0.02% Sodium Azide.
Storage Procedures
For short-term storage (up to 1 month), keep at 4°C. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Stability / Shelf Life
The antibody is stable for 12 months when stored at -20°C, and for 1 month at 4°C.
Applications
This antibody has undergone testing by ELISA and Western blot analysis, confirming its specificity and reactivity. As application requirements can differ, it is recommended to titrate the antibody for optimal results in each specific investigation. A starting dilution of 1:1000 is advised.
Synonyms
PARK7, Parkinson disease protein 7, Oncogene DJ-1,
Parkinson disease (autosomal recessive, early onset) 7.
Purification Method
PARK7 antibody was purified from mouse ascitic fluids by
protein-A affinity chromatography.
Type
Mouse Anti Human Monoclonal.
Immunogen
Anti-human PARK7 mAb, clone P1E12AT,
is derived from hybridization of mouse F0 myeloma cells with spleen cells from
BALB/c mice immunized with a recombinant human PARK7 protein 1-189 amino
acids purified from E. coli
Ig Subclass
Mouse
IgG2b heavy chain and k light chain.