NUP62CL Human

Nucleopurin 62kDa C-Terminal Like Human Recombinant

Cat. No.

BT20799

Source

Escherichia Coli.

Synonyms

FLJ20130, RP13-383K5.2, Nucleoporin-62 C-terminal-like protein, NUP62L, NUP62CL, Nucleopurin 62kDa C-Terminal Like.

Appearance

Sterile Filtered colorless solution.

Purity

Greater than 80.0% as determined by SDS-PAGE.

Usage

THE BioTek's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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Description

NUP62CL Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 95 amino acids (1-72 a.a) and having a molecular mass of 10.3kDa.
NUP62CL is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Product Specs

Introduction

Nucleopurin 62kDa C-Terminal Like, also known as NUP62CL, is a protein-coding gene. This gene encodes a protein containing a domain found in nucleoporins, which are glycoproteins located in nuclear pore complexes.

Description

Recombinant human NUP62CL, expressed in E. coli, is a single, non-glycosylated polypeptide chain. This protein consists of 95 amino acids (residues 1-72), with a molecular weight of 10.3 kDa. It includes a 23 amino acid His-tag at the N-terminus and is purified using proprietary chromatographic techniques.

Physical Appearance

Clear, colorless solution, sterile-filtered.

Formulation

This NUP62CL protein solution (1 mg/ml) is supplied in 20mM Tris-HCl buffer (pH 8.0), with 10% glycerol and 0.4M Urea.

Stability

For short-term storage (2-4 weeks), keep at 4°C. For extended storage, freeze at -20°C. Adding a carrier protein (0.1% HSA or BSA) is recommended for long-term storage. Avoid repeated freeze-thaw cycles.

Purity

Purity exceeds 80%, as determined by SDS-PAGE analysis.

Synonyms

FLJ20130, RP13-383K5.2, Nucleoporin-62 C-terminal-like protein, NUP62L, NUP62CL, Nucleopurin 62kDa C-Terminal Like.

Source

Escherichia Coli.

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMQFTSIS NSLTSTAAIG LSFTTSTTTT ATFTTNTTTT ITSGFTVNQN QLLSRGFENL VPYTSTVRFV FYMEK.

Product Science Overview

Structure and Function

NUP62CL is a small protein composed of 95 amino acids . It is non-glycosylated, meaning it does not have carbohydrate groups attached to it. The protein is involved in various cellular processes, including the regulation of nucleocytoplasmic transport, which is essential for maintaining cellular homeostasis and function.

Similarity to Other Proteins

NUP62CL shows close similarity to several other proteins, including:

NUP62: The C-terminal domain of NUP62, which is a part of the NPC.
Ran GTPase Activating Protein 1 (RANGAP1): Involved in the regulation of the Ran GTPase cycle, which is crucial for nucleocytoplasmic transport.
Putative RNA Binding Motif Protein 15B (RBM15B): Potentially involved in RNA binding and regulation.
Nuclear RNA Export Factor 1 (NXF1): Plays a role in the export of RNA from the nucleus to the cytoplasm .

Applications and Research

NUP62CL is used in various research applications, particularly in the study of nucleocytoplasmic transport and the function of the NPC. It is also utilized in the development of antibodies for immunohistochemistry and other immunological techniques. The protein is available in different forms and quantities from various suppliers, such as ProSpec and RayBiotech .

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NUP62CL Human

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Product Specs

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