LH Porcine

Luteinizing Hormone is a heterodimeric glycoprotein composed of two subunits: alpha and beta. The alpha subunit is common to other glycoprotein hormones such as Follicle-Stimulating Hormone (FSH), Thyroid-Stimulating Hormone (TSH), and Human Chorionic Gonadotropin (hCG). The beta subunit is unique to LH and confers its biological specificity.

In porcine species, LH has similar functions to those in other mammals. It stimulates the maturation of ovarian follicles, induces ovulation, and supports the formation and maintenance of the corpus luteum, which is essential for the production of progesterone .

Porcine Luteinizing Hormone can be extracted and purified from the pituitary glands of pigs. The extraction process typically involves homogenizing the pituitary tissue, followed by a series of purification steps such as ammonium sulfate precipitation, ion-exchange chromatography, and gel filtration chromatography. These steps help to isolate and purify the LH protein from other pituitary proteins and contaminants.

The biological activity of porcine LH is assessed through various in vitro and in vivo assays. In vitro assays may include measuring the hormone’s ability to stimulate steroidogenesis in cultured ovarian or testicular cells. In vivo assays often involve administering the hormone to animals and observing its effects on reproductive processes such as ovulation and luteinization.

Porcine LH is widely used in reproductive biology research to study the mechanisms of ovulation, follicular development, and luteal function. It is also used in veterinary medicine to induce ovulation and synchronize estrus in livestock. Additionally, porcine LH can be used in assisted reproductive technologies (ART) to enhance the success rates of in vitro fertilization (IVF) and other fertility treatments.