HIV 2 gp39 Antibody

The HIV-2 gp39, Polyclonal Rabbit Antibody is a research-grade antibody used in various immunological assays. This antibody is specifically designed to target the gp39 protein of the Human Immunodeficiency Virus type 2 (HIV-2). It is produced by immunizing rabbits with the gp39 protein, resulting in a polyclonal antibody that can recognize multiple epitopes on the target protein.

Human Immunodeficiency Virus type 2 (HIV-2) is a retrovirus that causes a condition leading to the failure of the immune system, making the body susceptible to opportunistic infections. HIV-2 is less virulent and less transmissible compared to HIV-1, but it still poses significant health risks.

The gp39 protein is a part of the envelope glycoproteins of HIV-2. It plays a crucial role in the virus’s ability to infect host cells and is involved in the fusion process between the viral envelope and the host cell membrane. The gp39 protein is immunoreactive, meaning it can elicit an immune response, making it a valuable target for antibody production.

Polyclonal antibodies are produced by immunizing an animal, in this case, a rabbit, with an antigen—in this context, the gp39 protein. The rabbit’s immune system responds by producing antibodies against the antigen. These antibodies are then collected from the rabbit’s serum. Since polyclonal antibodies are derived from multiple B cell clones, they can recognize and bind to multiple epitopes on the target antigen, providing a robust and versatile tool for research.

The HIV-2 gp39, Polyclonal Rabbit Antibody is used in various research applications, including:

• Enzyme-Linked Immunosorbent Assay (ELISA): This antibody can be used in ELISA to detect the presence of HIV-2 gp39 protein in samples.
• Western Blotting: It is used to identify and quantify the gp39 protein in different samples.
• Immunohistochemistry: The antibody can be used to visualize the localization of the gp39 protein in tissue samples.
• Flow Cytometry: It is used to analyze the expression of gp39 on the surface of cells.

The HIV-2 gp39, Polyclonal Rabbit Antibody is highly specific to the gp39 protein of HIV-2. It has been shown to be immunoreactive with E. coli-derived recombinant HIV-2 gp39 protein. Additionally, it exhibits cross-reactivity with the HIV-1 transmembrane envelope protein, making it a useful tool for studies involving both HIV-1 and HIV-2 .

The antibody is typically supplied as a sterile filtered solution and should be stored at -20°C to maintain its stability. It has a shelf life of one year when frozen and one month when stored in solution at 4°C .