HBsAg Antibody

Hepatitis-B Surface , Mouse antibody
Cat. No.
BT6633
Source
Synonyms
Appearance
Sterile Filtered solution.
Purity
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Shipped with Ice Packs
In Stock

Description

Product Specs

Introduction
HBsAg is the surface antigen of the Hepatitis-B-Virus (HBV). The virus capsid has different surface proteins than the rest of the virus. The antigen is a protein that specifically binds to one of these surface proteins. It is commonly referred to as the Australian Antigen.
Formulation
1mg/ml in PBS.
Physical Appearance
Sterile filtered solution.
Shipping Conditions
Antibody is shipped in liquid form with ice packs.
Storage Procedures
For periods up to 1 month store at 4°C, for longer periods, store at -20°C. Prevent freeze-thaw cycles.
Specificity

HBsAg antigen adw/ayw

Type
Mouse antibody Monoclonal.
Clone

PS38VN

Immunogen

HBsAg purified from human sera pool

Ig Subclass

Mouse IgG1.

Product Science Overview

Introduction

Hepatitis B is a viral infection that affects the liver and can lead to both acute and chronic diseases. The Hepatitis B virus (HBV) is a major global health problem, and it is particularly prevalent in certain regions, including parts of Asia and Africa. One of the key components in the study and diagnosis of HBV is the Hepatitis B surface antigen (HBsAg), which is a protein on the surface of the virus. Mouse antibodies against HBsAg are crucial tools in research and diagnostic applications.

Hepatitis B Surface Antigen (HBsAg)

HBsAg is the first serologic marker to appear in a new acute HBV infection. It can be detected as early as one week and as late as nine weeks after exposure to the virus, with an average of one month . The presence of HBsAg in the blood indicates that the person is infectious. The disappearance of HBsAg and the appearance of antibodies against HBsAg (anti-HBs) generally indicate recovery and immunity from re-infection .

Mouse Antibodies Against HBsAg

Mouse antibodies are widely used in research due to their specificity and ability to be produced in large quantities. The mouse anti-HBsAg antibody (clone 1834) is specific for the Hepatitis B virus surface antigen and recognizes subtypes ad and ay . These antibodies are often used in enzyme-linked immunosorbent assays (ELISA) to detect the presence of HBsAg in samples.

Applications of Mouse Anti-HBsAg Antibodies
  1. Diagnostic Testing: Mouse anti-HBsAg antibodies are used in diagnostic tests to detect HBV infection. These tests are crucial for identifying infected individuals and preventing the spread of the virus.
  2. Research: In research, these antibodies help in studying the structure and function of the Hepatitis B virus. They are also used in the development of vaccines and therapeutic agents.
  3. Therapeutic Monitoring: Monitoring the levels of HBsAg and anti-HBs in patients undergoing treatment for HBV infection helps in assessing the effectiveness of the treatment and the patient’s immune response.

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