Erythropoietin is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha-helical bundles . This protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis . Additionally, EPO has neuroprotective activity against various potential brain injuries and anti-apoptotic functions in several tissue types .
The Erythropoietin Mouse Anti Human (NYRhEPO) is a monoclonal antibody specifically designed to target human erythropoietin. This antibody is produced by immunizing mice with recombinant human erythropoietin, resulting in the generation of a specific immune response. The resulting monoclonal antibody is then purified and characterized for use in various research applications.
Clone and Immunogen: The clone used for this antibody is NYRhEPO, and the immunogen is recombinant human erythropoietin .
Ig Subclass: The antibody belongs to the Mouse IgG1 subclass .
Purification Method: The antibody is purified using ion exchange chromatography .
Formulation and Storage: The antibody is typically supplied in a lyophilized form and should be reconstituted with sterile water before use. For long-term storage, it is recommended to store the lyophilized antibody at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C .
The Erythropoietin Mouse Anti Human (NYRhEPO) antibody is widely used in various research applications, including: