CUEDC1 Human
CUE Domain Containing 1 Human Recombinant
Cat. No.
BT22975
Source
Escherichia Coli.
Synonyms
CUE Domain Containing 1, CUE Domain-Containing Protein 1.
Appearance
Sterile Filtered clear solution.
Purity
Greater
than 85% as determined by SDS-PAGE.
Usage
THE BioTek's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Shipped with Ice Packs 
In Stock 
Description
CUEDC1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 409 amino acids (1-386 a.a) and having a molecular mass of 44.6kDa.CUEDC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Specs
Introduction
CUE Domain Containing 1, also known as CUEDC1, contains one CUE domain. This domain is structurally similar to the ubiquitin-binding UBA domain and forms a domain-swapped dimer that enhances its interaction with ubiquitin, leading to high-affinity binding. CUE domains are found in proteins involved in various cellular processes, such as protein sorting and the degradation of misfolded proteins in the endoplasmic reticulum.
Description
Recombinant human CUEDC1 protein was expressed in E. coli and purified to a single, non-glycosylated polypeptide chain. This protein consists of 409 amino acids (residues 1-386), including a 23 amino acid His-tag fused to the N-terminus, and has a molecular weight of 44.6 kDa. Purification was achieved using proprietary chromatographic techniques.
Physical Appearance
A clear solution that has been sterilized by filtration.
Formulation
This CUEDC1 protein solution has a concentration of 0.25 mg/ml and is supplied in a buffer consisting of 20 mM Tris-HCl (pH 8.0), 0.15 M NaCl, 20% glycerol, and 1 mM DTT.
Stability
For short-term storage (up to 2-4 weeks), the product can be stored at 4°C. For long-term storage, it is recommended to store the product frozen at -20°C. To further enhance stability during long-term storage, adding a carrier protein like HSA or BSA (0.1%) is advisable. Repeated freezing and thawing of the product should be avoided.
Purity
The purity of this product is greater than 85% as determined by SDS-PAGE analysis.
Synonyms
CUE Domain Containing 1, CUE Domain-Containing Protein 1.
Source
Escherichia Coli.
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MGSMTSLFRR SSSGSGGGGT AGARGGGGGT AAPQELNNSR PARQVRRLEF
NQAMDDFKTM FPNMDYDIIE CVLRANSGAV DATIDQLLQM NLEGGGSSGG VYEDSSDSED SIPPEILERT
LEPDSSDEEP PPVYSPPAYH MHVFDRPYPL APPTPPPRID ALGSGAPTSQ RRYRNWNPPL LGNLPDDFLR ILPQQLDSIQ GNAGGPKPGS
GEGCPPAMAG PGPGDQESRW KQYLEDERIA LFLQNEEFMK ELQRNRDFLL ALERDRLKYE SQKSKSSSVA
VGNDFGFSSP VPGTGDANPA VSEDALFRDK LKHMGKSTRR KLFELARAFS EKTKMRKSKR KHLLKHQSLG AAASTANLLD DVEGHACDED FRGRRQEAPK VEEGLREGQ
Product Science Overview
Structure and Domain
Function
Recombinant Production
Physical and Chemical Properties
- Amino Acid Sequence: The recombinant human CUEDC1 protein consists of 409 amino acids, corresponding to the amino acids 1-386 of the native protein .
- Molecular Mass: The theoretical molecular weight of the recombinant protein is approximately 44.6 kDa .
- Purity: The protein is typically purified to a purity greater than 85%, as determined by SDS-PAGE .
Applications
Quick Inquiry
Personal Email Detected
Please use an institutional or corporate email address for inquiries. Personal email accounts ( such as Gmail, Yahoo, and Outlook) are not accepted. *
