Chlamydia W4-W5
Description
The E.coli derived recombinant 6xHis fusion at C-terminus protein contains Chlamydia Trachomatis MOMP protein epitopes, 191-354 amino acids.
Product Specs
Product Science Overview
The W4-W5 recombinant refers to a specific recombinant protein derived from Chlamydia trachomatis. This protein is produced using recombinant DNA technology, where the gene encoding the W4-W5 region of the bacterium is inserted into a host organism, typically E. coli, to produce the protein in large quantities . The W4-W5 region is part of the major outer membrane protein (MOMP) of Chlamydia trachomatis, which plays a crucial role in the bacterium’s ability to infect host cells .
The W4-W5 recombinant protein is significant in the development of vaccines against Chlamydia trachomatis. Researchers have identified novel antigens, including the W4-W5 region, that elicit immune responses in humans. These antigens have been shown to be immunogenic and protective when used in vaccine formulations . The development of a vaccine against Chlamydia trachomatis is crucial, as current treatments with antibiotics do not address the established pathology and often fail to prevent asymptomatic infections .
Recombinant proteins like W4-W5 are used extensively in research to study the immune response to Chlamydia trachomatis and to develop diagnostic tools and vaccines. The high purity and reproducibility of these recombinant proteins make them ideal for use in immunization protocols and generating specific antibodies .
