C16ORF53 Human
PAXIP1-associated protein 1, PTIP-associated protein 1, PA1, C16orf53, GAS.
Description
C16ORF53 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 274 amino acids (1-254 a.a.) and having a molecular mass of 29.9kDa (Molecular weight on SDS-PAGE will appear higher).
C16ORF53 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Specs
PAXIP1-associated protein 1, PTIP-associated protein 1, PA1, C16orf53, GAS.
MGSSHHHHHH SSGLVPRGSH MSLARGHGDT AASTAAPLSE EGEVTSGLQA LAVEDTGGPS ASAGKAEDEG EGGREETERE GSGGEEAQGE VPSAGGEEPA EEDSEDWCVP CSDEEVELPA DGQPWMPPPS EIQRLYELLA AHGTLELQAE ILPRRPPTPE AQSEEERSDE EPEAKEEEEE KPHMPTEFDF DDEPVTPKDS LIDRRRTPGS SARSQKREAR LDKVLSDMKR HKKLEEQILR TGRDLFSLDS EDPSPASPPL RSSGSSLFPR QRKY.
Product Science Overview
Chromosome 16 Open Reading Frame 53 (C16orf53) is a gene located on the 16th chromosome in humans. This gene encodes a protein that is involved in various cellular processes. The recombinant form of this protein, produced through biotechnological methods, is used in research to understand its function and potential applications in medicine.
Chromosome 16 is one of the 23 pairs of chromosomes in humans. It spans approximately 90 million base pairs and represents just under 3% of the total DNA in cells . This chromosome contains a significant number of genes, including those involved in metabolic pathways, immune response, and developmental processes.
The C16orf53 gene is one of the many open reading frames (ORFs) on chromosome 16. An open reading frame is a sequence of DNA that has the potential to be translated into a protein. The C16orf53 gene encodes a protein that consists of 274 amino acids and has a molecular mass of approximately 29.9 kDa . This protein is non-glycosylated and is produced in Escherichia coli (E. coli) for research purposes.
The recombinant form of C16orf53 is produced using E. coli expression systems. The gene encoding C16orf53 is inserted into a plasmid vector, which is then introduced into E. coli cells. These cells are cultured under specific conditions to express the protein. The recombinant protein is then purified using chromatographic techniques to ensure its purity and functionality .
The recombinant C16orf53 protein is used in various research applications, including:
- Functional Studies: Researchers use the recombinant protein to study its role in cellular processes and its interaction with other proteins.
- Disease Research: Understanding the function of C16orf53 can provide insights into its involvement in diseases and potential therapeutic targets.
- Biotechnological Applications: The recombinant protein can be used in the development of diagnostic tools and therapeutic agents.
