ACYP1 Human
Acylphosphatase 1 Human Recombinant
Cat. No.
BT27104
Source
Escherichia Coli.
Synonyms
Acylphosphatase-1, Acylphosphatase, erythrocyte isozyme, Acylphosphatase, organ-common type isozyme, Acylphosphate phosphohydrolase 1, ACYP1, ACYPE.
Appearance
Sterile Filtered colorless solution.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Usage
THE BioTek's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Shipped with Ice Packs 
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Description
ACYP1 Human Recombinant fused with a 23 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 122 amino acids (1-99 a.a.) and having a molecular mass of 13.6kDa. The ACYP1 is purified by proprietary chromatographic techniques.
Product Specs
Introduction
Erythrocyte acylphosphatase (ACYP1) is an enzyme found in the cytosol that breaks down acylphosphates by hydrolyzing their carboxyl-phosphate bond. Two isoenzymes of acylphophatase exist: ACYP1 and ACYP2. Despite sharing 60% homology and having the same substrate specificity, ACYP1 exhibits higher catalytic activity compared to ACYP2.
Description
Recombinant human ACYP1, expressed in E. coli, is a single, non-glycosylated polypeptide chain with a molecular weight of 13.6 kDa. It comprises 122 amino acids, including a 23 amino acid His tag at the N-terminus (amino acids 1-99). Purification of ACYP1 is achieved through proprietary chromatographic techniques.
Physical Appearance
Clear, colorless solution that has been sterilized by filtration.
Formulation
The ACYP1 solution is provided at a concentration of 1 mg/ml and is formulated in a buffer containing 20mM Tris-HCl (pH 8.0), 20% glycerol, 0.1M NaCl, and 1mM DTT.
Stability
For short-term storage (2-4 weeks), keep the ACYP1 vial refrigerated at 4°C. For extended storage, freeze the solution at -20°C. To enhance long-term stability, consider adding a carrier protein (0.1% HSA or BSA) to the solution. Repeated freezing and thawing cycles should be avoided.
Purity
The purity of ACYP1 is determined to be greater than 90% by SDS-PAGE analysis.
Synonyms
Acylphosphatase-1, Acylphosphatase, erythrocyte isozyme, Acylphosphatase, organ-common type isozyme, Acylphosphate phosphohydrolase 1, ACYP1, ACYPE.
Source
Escherichia Coli.
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MGSMAEGNTL ISVDYEIFGK VQGVFFRKHT QAEGKKLGLV GWVQNTDRGT VQGQLQGPIS KVRHMQEWLE TRGSPKSHID KANFNNEKVI LKLDYSDFQI VK.
Product Science Overview
Classification and Isoenzymes
Biological Properties and Expression Patterns
Tissue Distribution and Biological Functions
ACYP1 is widely distributed in the human body, with notable expression in erythrocytes . Its primary biological function is to catalyze the hydrolysis of acylphosphates, which is essential for cellular energy metabolism . This enzymatic activity helps maintain cellular homeostasis and energy balance.
Roles in Immune Responses and Pathogen Recognition
Modes of Action and Mechanisms with Other Molecules and Cells
Binding Partners and Downstream Signaling Cascades
Regulatory Mechanisms
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