WIBG Human
within BCGN Homolog Human Recombinant
Cat. No.
BT357
Source
Escherichia Coli.
Synonyms
PYM, Partner of Y14 and mago, MGC13064, WIBG, BCGN Homolog, Protein wibg homolog.
Appearance
Sterile filtered colorless solution.
Purity
Greater than 85.0% as determined by SDS-PAGE.
Usage
THE BioTek's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description
WIBG Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 212 amino acids (1-204 a.a.) and having a molecular mass of 23.7 kDa. The WIBG is fused to 8 amino acid His-Tag at C-terminus and purified by proprietary chromatographic techniques.
Product Specs
Introduction
WIBG, a cooperating partner of Mago-Y14, forms the Mago-Y14 heterodimer, a crucial protein in the exon junction complex (EJC). Deposited on mRNAs during splicing, the EJC influences post-splicing mRNA metabolism. WIBG, a cytoplasmic RNA-binding protein, is excluded from the nucleus by Crm1 and interacts directly with Mago-Y14 through its N-terminal domain.
Description
Recombinant Human WIBG, produced in E. coli, is a single, non-glycosylated polypeptide chain of 212 amino acids (1-204 a.a.) with a molecular weight of 23.7 kDa. An 8 amino acid His-Tag is fused to the C-terminus. Purification is achieved using proprietary chromatographic techniques.
Physical Appearance
A clear, colorless solution, sterile-filtered.
Formulation
WIBG Human solution in 20mM Tris buffer (pH 8.0), containing 0.1M NaCl and 10% glycerol.
Stability
For short-term storage (2-4 weeks), store at 4°C. For longer periods, store frozen at -20°C. Adding a carrier protein (0.1% HSA or BSA) is recommended for long-term storage. Avoid repeated freeze-thaw cycles.
Purity
Purity exceeds 85.0% as determined by SDS-PAGE analysis.
Synonyms
PYM, Partner of Y14 and mago, MGC13064, WIBG, BCGN Homolog, Protein wibg homolog.
Source
Escherichia Coli.
Amino Acid Sequence
MEAAGSPAAT ETGKYIASTQ RPDGTWRKQR RVKEGYVPQE EVPVYENKYV KFFKSKPELP PGLSPEATAP VTPSRPEGGE PGLSKTAKRN LKRKEKRRQQ QEKGEAEALS RTLDKVSLEE TAQLPSAPQG SRAAPTAASD QPDSAATTEK AKKIKNLKKK LRQVEELQQR IQAGEVSQPS KEQLEKLARR RALEEELEDL ELGLLEHHHH HH.
Product Science Overview
Background of “within BCGN Homolog (Human Recombinant)”
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