SST
Somatostatin
Cat. No.
BT17407
Source
Synonyms
Growth hormone release-inhibiting factor, SST, SMS, SMST, GHIH.
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity
Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Shipped with Ice Packs 
In Stock 
Description
Somatostatin Synthetic is a single, non-glycosylated polypeptide chain containing 14 amino acids, having a molecular mass of 1637.9 Dalton and a Molecular formula of C76H104N18O19S2. The CAS# is 38916-34-6.
Product Specs
Introduction
Somatostatin, also known as growth hormone inhibiting hormone (GHIH) or somatotropin release-inhibiting hormone (SRIF), is a peptide hormone that regulates the endocrine system. It influences neurotransmission and cell proliferation by interacting with G-protein-coupled somatostatin receptors and inhibiting the release of several secondary hormones. Somatostatin exists in two active forms, generated by alternative cleavage of a single preproprotein: one consisting of 14 amino acids and the other of 28 amino acids.
Description
Synthetic Somatostatin is a single, non-glycosylated polypeptide chain composed of 14 amino acids. It has a molecular weight of 1637.9 Daltons and a molecular formula of C76H104N18O19S2. The CAS registry number for this compound is 38916-34-6.
Physical Appearance
Sterile Filtered White Lyophilized Powder
Formulation
The protein has been lyophilized without the addition of any other substances.
Solubility
To reconstitute the lyophilized Somatostatin, it is recommended to dissolve it in sterile 18MΩ-cm H2O at a concentration not lower than 100 µg/ml. This solution can be further diluted with other aqueous solutions as needed.
Stability
Lyophilized Somatostatin (SST) remains stable at room temperature for up to 3 weeks. However, for long-term storage, it is recommended to store it in a desiccated state below -18°C. Once reconstituted, Somatostatin should be stored at 4°C for 2-7 days. For extended storage periods, it is advisable to store it below -18°C. To ensure optimal stability during long-term storage, consider adding a carrier protein like 0.1% HSA or BSA. It's important to minimize freeze-thaw cycles.
Purity
The purity of this product is greater than 98.0%, as determined by the following methods:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Synonyms
Growth hormone release-inhibiting factor, SST, SMS, SMST, GHIH.
Amino Acid Sequence
Ala-Gly-Cys-Lys-Asn-Phe- Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH.
Product Science Overview
Structure and Forms
Production and Distribution
Somatostatin is produced by various tissues in the body, primarily in the nervous and digestive systems. Key production sites include:
Functions
The primary function of somatostatin is to inhibit the release of other hormones and regulate various physiological processes. Some of its key functions include:
- Inhibition of Hormone Secretion: Somatostatin inhibits the secretion of several hormones, including growth hormone, thyroid-stimulating hormone (TSH), and insulin .
- Regulation of Gastrointestinal Activity: It slows down the digestive process by inhibiting the secretion of gastric acid and digestive enzymes .
- Cell Proliferation: Somatostatin prevents the rapid reproduction of normal and tumor cells .
Receptors
Clinical Significance
Somatostatin and its synthetic analogs are used in the treatment of various medical conditions, including:
Quick Inquiry
Personal Email Detected
Please use an institutional or corporate email address for inquiries. Personal email accounts ( such as Gmail, Yahoo, and Outlook) are not accepted. *
