SELANK
Greater than 97.0% as determined by analysis by RP-HPLC.
Description
SELANK Synthetic is a single, non-glycosylated polypeptide chain containing 7 amino acids, having a molecular mass of 751.89 Dalton and a Molecular formula of C33H57N11O9.
Product Specs
H-Thr-Lys-Pro-Arg-Pro-Gly-Pro-OH.
Product Science Overview
Selank mimics many of the effects of tuftsin, which is known for its immunomodulatory properties. It has been shown to modulate the expression of Interleukin-6 (IL-6) and affect the balance of T helper cell cytokines . Additionally, Selank influences the concentration of monoamine neurotransmitters and induces the metabolism of serotonin . It also rapidly elevates the expression of brain-derived neurotrophic factor (BDNF) in the hippocampus .
Selank has several notable pharmacological effects:
- Anxiolytic Effects: Selank has been found to produce anxiolytic (anti-anxiety) effects without the sedative and cognitive side effects commonly associated with traditional anxiolytics like benzodiazepines .
- Cognitive Enhancement: It is known for its nootropic effects, which include improving cognitive functions such as memory and learning .
- Neuroprotective Properties: Selank enhances brain health and resilience against cognitive decline by promoting the growth, differentiation, and survival of neurons .
In clinical trials, Selank has shown to provide sustained nootropic and anxiolytic effects, making it useful for the treatment of generalized anxiety disorder (GAD) . Unlike traditional anxiety treatments, Selank does not have sedating or negative cognitive side effects and does not cause addiction or withdrawal problems .
Selank is closely related to another nootropic drug, Semax, which was also developed by the Institute of Molecular Genetics in Russia . Both drugs share similar mechanisms of action and therapeutic effects, but Selank is particularly noted for its rapid onset of action when administered as a nasal spray .
