SBDS Antibody
Shwachman-Bodian-Diamond Syndrome, Mouse Anti Human
Cat. No.
BT30565
Source
Synonyms
SDS, SWDS, Shwachman-Bodian-Diamond syndrome, Ribosome Maturation protein SBDS.
Appearance
Purity
Usage
THE BioTek's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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In Stock 
Description
Product Specs
Introduction
SBDS (Shwachman-Bodian-Diamond syndrome) protein is a highly conserved protein found in various organisms, including archaea, vertebrates, and plants. It plays a crucial role in RNA metabolism, particularly in the production of the 60S ribosomal subunit, a vital component of ribosomes responsible for protein synthesis. SBDS is also involved in activating ribosomes for translation. Mutations in the SBDS gene lead to Shwachman-Diamond syndrome, a rare genetic disorder inherited in an autosomal recessive manner.
Formulation
The antibody is supplied in a solution containing 1mg/ml of antibody in phosphate-buffered saline (PBS) at pH 7.4, with 0.02% sodium azide as a preservative and 10% glycerol as a stabilizer.
Storage Procedures
For short-term storage (up to 1 month), keep the antibody at 4°C. For long-term storage, it is recommended to store the antibody at -20°C. Avoid repeated freeze-thaw cycles to maintain antibody stability.
Stability / Shelf Life
The antibody has a shelf life of 12 months when stored at -20°C and 1 month when stored at 4°C.
Synonyms
SDS, SWDS, Shwachman-Bodian-Diamond syndrome, Ribosome Maturation protein SBDS.
Purification Method
SBDS antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Type
Mouse Anti Human Monoclonal.
Clone
PAT1E8AT.
Immunogen
Anti-human SBDS mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human SBDS amino acids 1-250 purified from E. coli.
Ig Subclass
Mouse IgG2b heavy chain and kappa light chain.
Product Science Overview
Mouse Anti-Human Antibodies
Mouse anti-human antibodies are secondary antibodies generated by immunizing mice with human immunoglobulins. These antibodies are used in various applications, including detection, sorting, and purification of human proteins .
Applications
- Detection: Used in techniques like ELISA, Western Blot, and Immunohistochemistry to detect human proteins .
- Sorting and Purification: These antibodies help in sorting cells and purifying proteins from human samples .
Types
Mouse anti-human antibodies can be conjugated with various labels such as HRP, AP, fluorescence, and biotin to enhance detection sensitivity .
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