REXO2 Antibody

REXO2 is specific for small single-stranded RNA and DNA oligomers, primarily those that are five nucleotides or less in length . This specificity allows REXO2 to participate in the degradation of small RNA and DNA fragments, which is essential for maintaining cellular homeostasis and preventing the accumulation of potentially harmful nucleic acid fragments.

The enzyme is involved in the resistance of human cells to ultraviolet C (UV-C) induced cell death through its role in the DNA repair process . By participating in the repair of damaged DNA, REXO2 helps to maintain the integrity of the genome and prevent mutations that could lead to diseases such as cancer.

The Mouse Anti Human REXO2 Antibody is a monoclonal antibody that is used in various research applications to study the function and regulation of REXO2. This antibody is derived from the hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice that have been immunized with a recombinant human REXO2 protein .

The antibody is purified from mouse ascitic fluids using protein-A affinity chromatography, ensuring high specificity and reactivity . It is typically formulated in a sterile filtered colorless solution containing phosphate-buffered saline (PBS), glycerol, and sodium azide .

The Mouse Anti Human REXO2 Antibody is widely used in laboratory research for various applications, including enzyme-linked immunosorbent assay (ELISA), Western blot analysis, and immunohistochemistry . These techniques allow researchers to detect and quantify REXO2 in different biological samples, providing valuable insights into its role in cellular processes.

For optimal stability, the antibody should be stored at 4°C for short-term use (up to one month) and at -20°C for long-term storage (up to 12 months) . It is important to avoid freeze-thaw cycles to maintain the antibody’s activity and specificity.