RABL5 Human
RAB, Member RAS Oncogene Family-Like 5 Human Recombinant
Cat. No.
BT10319
Source
E.coli.
Synonyms
Rab-like protein 5 isoform a, Rab-like protein 5, RABL5, RAB, Member RAS Oncogene Family-Like 5.
Appearance
Sterile Filtered colorless solution.
Purity
Greater than 95% as determined by SDS-PAGE.
Usage
THE BioTek's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description
RABL5 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 208 amino acids (1-185) and having a molecular mass of 23.2 kDa. RABL5 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Specs
Introduction
RABL5 (RAB, Member RAS Oncogene Family-Like 5) is a small GTP-binding protein belonging to the Ras superfamily. This superfamily consists of various subfamilies, including R-Ras, Rap, Ral/Rec, and Rho/Rab. Rab proteins play a crucial role in the transportation of newly synthesized proteins. This process involves moving these proteins from the endoplasmic reticulum through the Golgi complex to secretory vesicles using carrier vesicles, a process requiring Rab protein functionality.
Description
Recombinant RABL5 Human, produced in E. coli, is a single, non-glycosylated polypeptide chain. It consists of 208 amino acids (amino acids 1-185) and has a molecular weight of 23.2 kDa. The protein includes a 23 amino acid His-tag fused at the N-terminus and is purified using proprietary chromatographic techniques.
Physical Appearance
A clear, colorless solution that has been sterile filtered.
Formulation
The RABL5 solution has a concentration of 0.5 mg/mL and contains 20 mM Tris-HCl buffer with a pH of 8.0, 0.1 M NaCl, 10% glycerol, and 1 mM DTT.
Stability
For short-term storage (2-4 weeks), keep at 4°C. For longer storage, freeze at -20°C. Adding a carrier protein (0.1% HSA or BSA) is recommended for long-term storage. Avoid repeated freeze-thaw cycles.
Purity
Purity is greater than 95% as determined by SDS-PAGE analysis.
Synonyms
Rab-like protein 5 isoform a, Rab-like protein 5, RABL5, RAB, Member RAS Oncogene Family-Like 5.
Source
E.coli.
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MGSMLKAKIL FVGPCESGKT VLANFLTESS DITEYSPTQG VRILEFENPH VTSNNKGTGC EFELWDCGGD AKFESCWPAL MKDAHGVVIV FNADIPSHRK EMEMWYSCFV QQPSLQDTQC MLIAHHKPGS GDDKGSLSLS PPLNKLKLVH SNLEDDPEEI RMEFIKYLKS IINSMSESRD REEMSIMT.
Product Science Overview
Gene and Protein Information
Biological Role
Clinical Significance
Recombinant RABL5
Recombinant RABL5 is produced using recombinant DNA technology, which involves inserting the RABL5 gene into a suitable expression system to produce the protein in large quantities. This recombinant protein is used in various research applications to study its function and role in disease processes .
Applications in Research
Recombinant RABL5 is utilized in:
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