RAB1A Human
THE BioTek's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Description
RAB1A is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Specs
Product Science Overview
RAB1A plays a crucial role in regulating vesicular protein transport from the ER to the Golgi compartment and subsequently to the cell surface . It is involved in the secretion of interleukin-8 (IL-8) and growth hormone . Additionally, RAB1A is required to modulate the compacted morphology of the Golgi .
RAB1A exhibits general cytoplasmic expression and is localized to the endoplasmic reticulum and cytosol . It has low tissue specificity, meaning it is expressed in various tissues including the cerebral cortex, cerebellum, basal ganglia, hypothalamus, midbrain, amygdala, choroid plexus, hippocampal formation, spinal cord, retina, thyroid gland, parathyroid gland, adrenal gland, pituitary gland, lung, salivary gland, esophagus, tongue, stomach, duodenum, small intestine, colon, rectum, liver, gallbladder, pancreas, kidney, urinary bladder, testis, epididymis, seminal vesicle, prostate, vagina, ovary, fallopian tube, endometrium, cervix, placenta, breast, heart muscle, smooth muscle, skeletal muscle, adipose tissue, skin, appendix, spleen, lymph node, tonsil, bone marrow, and thymus .
The RAB1A gene is of significant interest in research due to its role in intracellular trafficking and its association with various diseases. Understanding the function and regulation of RAB1A can provide insights into the mechanisms of vesicular transport and its implications in health and disease.
For more detailed information, you can refer to the GeneCards entry on RAB1A and the Human Protein Atlas.
