PCP4L1 Human
Purkinje Cell Protein 4 Like 1 Human Recombinant
Cat. No.
BT5331
Source
Escherichia Coli.
Synonyms
PCP4L1, Purkinje Cell Protein 4 Like 1, IQM1, PCP4-Like Protein 1, Purkinje Cell Protein 4-Like Protein 1.
Appearance
Sterile Filtered colorless solution.
Purity
Greater than 85.0% as determined by SDS-PAGE.
Usage
THE BioTek's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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Description
PCP4L1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 91 amino acids (1-68 a.a) and having a molecular mass of 9.9kDa (Molecular size on SDS-PAGE will appear higher).
PCP4L1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
PCP4L1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Specs
Introduction
As a member of the PCP4 family, Purkinje cell protein 4-like protein 1 (PCP4L1) possesses an IQ domain and plays a role in protein coding.
Description
Recombinant PCP4L1, of human origin, is produced in E. coli. This non-glycosylated polypeptide chain consists of 91 amino acids (specifically, amino acids 1 through 68), resulting in a molecular mass of 9.9 kDa. Note that the molecular size observed on SDS-PAGE might appear larger. A 23 amino acid His-tag is fused to the N-terminus of PCP4L1, and purification is achieved through proprietary chromatographic techniques.
Physical Appearance
The solution is colorless and has been sterilized through filtration.
Formulation
The PCP4L1 protein solution has a concentration of 0.5 mg/ml and is prepared in a buffer containing 20 mM Tris-HCl (pH 8.0), 0.15 M NaCl, and 20% glycerol.
Stability
For optimal storage, refrigerate the vial at 4°C if the entire contents will be used within 2-4 weeks. For prolonged storage, freeze at -20°C. The addition of a carrier protein (0.1% HSA or BSA) is recommended for long-term storage. Repeated freezing and thawing should be avoided.
Purity
SDS-PAGE analysis indicates a purity exceeding 85.0%.
Synonyms
PCP4L1, Purkinje Cell Protein 4 Like 1, IQM1, PCP4-Like Protein 1, Purkinje Cell Protein 4-Like Protein 1.
Source
Escherichia Coli.
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MGSMSELNTK TSPATNQAAG QEEKGKAGNV KKAEEEEEID IDLTAPETEK AALAIQGKFR RFQKRKKDPS S.
Product Science Overview
Gene and Protein Information
- Gene Symbol: PCP4L1
- Aliases: IQM1, Purkinje Cell Protein 4-Like Protein 1
- Location: Chromosome 1q23.3
- Protein Size: Small neuronal protein
Function and Importance
PCP4L1 is primarily expressed in the nervous system and is involved in various cellular processes, including calcium signaling and neuronal differentiation . The protein’s ability to bind calmodulin suggests it plays a role in modulating calcium-dependent signaling pathways, which are crucial for neuronal function and development .
Associated Diseases
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