OXLD1 Human

Oxidoreductase-Like Domain Containing 1 Human Recombinant
Cat. No.
BT4121
Source
Escherichia Coli.
Synonyms
C17orf90, Oxidoreductase-like domain-containing protein 1, OXLD1.
Appearance
Sterile Filtered colorless solution.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Usage
THE BioTek's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Shipped with Ice Packs
In Stock

Description

OXLD1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 125 amino acids (46-147a.a) and having a molecular mass of 13.4kDa.
OXLD1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Product Specs

Introduction
Oxidoreductase-Like Domain Containing 1, also known as OXLD1, is a protein-coding gene associated with the lncRNA class. OXLD1 contains one oxidoreductase-like domain.
Description
Recombinant human OXLD1 protein produced in E. coli. It is a single, non-glycosylated polypeptide chain containing 125 amino acids (residues 46-147) and has a molecular mass of 13.4 kDa. OXLD1 is fused to a 23 amino acid His-tag at the N-terminus and purified using proprietary chromatographic techniques.
Physical Appearance
A sterile, colorless, and clear solution.
Formulation
The OXLD1 protein solution has a concentration of 0.25 mg/ml and is supplied in a buffer containing 20 mM Tris-HCl (pH 8.0), 0.15 M NaCl, 50% glycerol, and 1 mM DTT.
Stability
For short-term storage (up to 2-4 weeks), store the protein at 4°C. For long-term storage, freeze the protein at -20°C. Adding a carrier protein (0.1% HSA or BSA) is recommended for long-term storage. Avoid repeated freeze-thaw cycles.
Purity
The purity is determined to be greater than 90% by SDS-PAGE analysis.
Synonyms
C17orf90, Oxidoreductase-like domain-containing protein 1, OXLD1.
Source
Escherichia Coli.
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MGSPGAQAPD GRRKFGTDHV EVGSQAGADG TRPPKASLPP ELQPPTNCCM SGCPNCVWVE YADRLLQHFQ DGGERALAAL EEHVADENLK AFLRMEIRLH TRCGG.

Product Science Overview

Gene and Protein Information
  • Gene Symbol: OXLD1
  • Chromosomal Location: Chromosome 17
  • Protein Name: Oxidoreductase-Like Domain-Containing Protein 1
  • UniProt ID: Q5BKU9
Function and Biological Role

The primary function of the OXLD1 protein is related to its oxidoreductase activity. Oxidoreductases are enzymes that catalyze oxidation-reduction reactions, which are essential for various metabolic pathways. These reactions involve the transfer of electrons from one molecule (the reductant) to another (the oxidant). The OXLD1 protein is believed to participate in these processes, although its specific substrates and mechanisms are still under investigation.

Associated Diseases

Research has linked mutations or dysregulation of the OXLD1 gene to certain medical conditions. Notably, Mitral Valve Insufficiency and Mitral Valve Disease have been associated with abnormalities in this gene . These conditions affect the heart’s mitral valve, leading to improper blood flow and potential complications.

Recombinant Protein

The recombinant form of OXLD1, often produced in E. coli expression systems, is used in various research applications. This recombinant protein can be utilized in blocking assays and control experiments to study its function and interactions . The recombinant OXLD1 protein typically includes a His-ABP tag for purification and detection purposes.

Research and Applications

OXLD1 is a subject of ongoing research due to its potential implications in health and disease. Scientists are exploring its role in cellular metabolism, redox balance, and its involvement in pathological conditions. Understanding the function and regulation of OXLD1 could lead to new therapeutic targets for diseases associated with oxidative stress and redox imbalances.

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